F6377

Fluorescein sodium salt

Powder

• Sinonimo/i: Acid Yellow 73, D&C;Yellow No. 8, NaFl, NaFluo, Sodium fluorescein, Uranine
• Formula empirica (notazione di Hill): C₂₀H₁₀Na₂O₅
• Numero CAS: 518-47-8
• Peso molecolare: 376.27
• Colour Index: 45350
• Beilstein: 3833041
• Numero CE: 208-253-0
• Numero MDL: MFCD00167039
• Codice UNSPSC: 12171500
• ID PubChem: 24894907
• NACRES: NA.47

Proprietà

• product name: Fluorescein sodium salt, used as fluorescent tracer
• Livello qualitativo: 200
• Forma fisica: powder
• Colore: orange to brown
• pH: 8.3 (20 °C, 10 g/L)
• Punto di fusione: >300 °C
• Solubilità: H₂O: 1 mg/mL
• Densità: 0.78 g/cm³ at 29.6 °C (85.3 °F at 699.7 hPa)
• Fluorescenza: λ_ex 460 nm; λ_em 515 nm(lit.)
• applicazioni: diagnostic assay manufacturing; hematology; histology
• Temperatura di conservazione: room temp
• Stringa SMILE: [Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1
• InChI: 1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2; RGPLGPBQJOQFJS-UHFFFAOYSA-L

Descrizione

Descrizione generale

Fluorescein is a xanthene dye and is a common labeling agent in biology.

Applicazioni

Fluorescein sodium salt has been used as a solute to study microvessel permeability. It has been used as a test molecule to study blood barrier penetration.

Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius. Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes. Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 423.7 °F - Pensky-Martens closed cup
• Punto d’infiammabilità (°C): 217.6 °C - Pensky-Martens closed cup
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)