Passa al contenuto
Merck
Tutte le immagini(4)

Documenti fondamentali

Visualizza tutta la documentazione

M1275

Sigma-Aldrich

Naproxen sodium

98.0-102.0%

Sinonimo/i:

(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid sodium salt

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(4)

About This Item

Formula empirica (notazione di Hill):
C14H13NaO3
Numero CAS:
26159-34-2
Peso molecolare:
252.24
Numero CE:
247-486-2
Numero MDL:
MFCD00058507
Codice UNSPSC:
12352200
ID PubChem:
57654352
NACRES:
NA.77

Origine biologica

synthetic (organic)

Livello qualitativo

200

Saggio

98.0-102.0%

Forma fisica

powder

Solubilità

water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

Ideatore

Bayer

Stringa SMILE

[Na+].COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O

InChI

1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
CDBRNDSHEYLDJV-FVGYRXGTSA-M

Informazioni sul gene

human ... PTGS1(5742) , PTGS2(5743)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Naproxen belongs to phenylacetic acid class of Non-steroidal anti-inflammatory drugs (NSAIDs).

Applicazioni

Naproxen sodium has been used to evaluate the thermodynamics of biomolecular interaction with bovine and human serum albumin. It has also been used to evaluate its efficiency in reducing the response of spinal dorsal horn neurons to noxious knee joint rotation.

Azioni biochim/fisiol

Naproxen binds preferably to serum albumin. The S-enantiomer of naproxen is 28-fold more potential as an anti-inflammatory drug compared to the R-isomer. The R-isomer is found to be a liver toxin and causes gastrointestinal disorders.
Cyclooxygenase (Prostaglandin H synthase 1 and 2) inhibitor.

Caratteristiche e vantaggi

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H360

Classi di pericolo

Acute Tox. 4 Oral - Repr. 1A

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 8

1 of 8

Naproxen Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1040

Naproxen

Naproxen United States Pharmacopeia (USP) Reference Standard

USP

1457301

Naproxen

L-(−)-Xylose, mixture of anomers ≥99%

Sigma-Aldrich

851590

L-(−)-Xylose, mixture of anomers

(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid 98%

Sigma-Aldrich

284785

(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid

Ketoprofen ≥98% (TLC)

Sigma-Aldrich

K1751

Ketoprofen

Diclofenac

Sigma-Aldrich

D6899

Diclofenac

Sulindac ≥98.0%

Sigma-Aldrich

S8139

Sulindac

Ibuprofen sodium salt ≥98% (GC)

Supelco

I1892

Ibuprofen sodium salt

Binding thermodynamics of Diclofenac and Naproxen with human and bovine serum albumins: A calorimetric and spectroscopic study
Bou-Abdallah F, et al.
The Journal of Chemical Thermodynamics, 103, 299-309 (2016)
Margarita Valero et al.
Langmuir : the ACS journal of surfaces and colloids, 26(13), 10561-10571 (2010-05-15)
The associative structures between F127 Pluronic micelles and four drugs, namely, lidocaine (LD), pentobarbital sodium salt (PB), sodium naproxen (NP), and sodium salicylate (SAL), were studied by small-angle neutron scattering (SANS). Different outcomes for the micellar aggregates are observed, which
Arın Gül Dal et al.
Journal of analytical methods in chemistry, 2014, 352698-352698 (2014-10-09)
Simple and rapid capillary zone electrophoretic method was developed and validated in this study for the determination of piroxicam in tablets. The separation of piroxicam was conducted in a fused-silica capillary by using 10 mM borate buffer (pH 9.0) containing 10%
Matteo Morotti et al.
European journal of obstetrics, gynecology, and reproductive biology, 179, 63-68 (2014-06-27)
Evaluate patient satisfaction at 6-month treatment in women with symptomatic rectovaginal endometriosis and migraine without aura with (progestogen-only contraceptive pill, POP versus sequential combined oral contraceptives, COC) STUDY DESIGN: A patient preference trial including 144 women (82 in the group
Jason A Miranda et al.
PloS one, 9(8), e106108-e106108 (2014-08-27)
Sensory processing in the spinal cord during disease states can reveal mechanisms for novel treatments, yet very little is known about pain processing at this level in the most commonly used animal models of articular pain. Here we report a
Visualizza tutti i documenti correlati

Chromatograms

application for HPLC

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.