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Documenti fondamentali

L8901

Sigma-Aldrich

Lys-Lys-Lys

≥97% (TLC)

Sinonimo/i:

Trilysine

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About This Item

Formula empirica (notazione di Hill):
C18H38N6O4
Numero CAS:
Peso molecolare:
402.53
Numero MDL:
Codice UNSPSC:
12352209
ID PubChem:
NACRES:
NA.26

Nome del prodotto

Lys-Lys-Lys, ≥97% (TLC)

Livello qualitativo

Saggio

≥97% (TLC)

Stato

powder

Composizione

Peptide content, ~60%

Colore

white to off-white

Temperatura di conservazione

−20°C

Stringa SMILE

NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)
WBSCNDJQPKSPII-UHFFFAOYSA-N

Amino Acid Sequence

Lys-Lys-Lys

Applicazioni

Short poly-L-lysines polypeptides such as trilysine (tri-L-lysine, lys3); tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Journal of the American Chemical Society, 128(17), 5703-5710 (2006-04-28)
Formation of DNA-protein cross-links involving the initial formation of a guanine radical cation was investigated. For this purpose, riboflavin-mediated photosensitization of a TGT oligonucleotide in aerated aqueous solution in the presence of the KKK tripeptide was performed. We have shown
Yudan Ma et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(47), 13135-13140 (2009-10-27)
Single-strand oligo-DNA-modified Au nanoparticles (AuNPs) undergo aggregation in the presence of poly(L-lysine) (PLL), which is attributed to the interactions between the oligo-DNA and PLL. These interactions between the oligo-DNA and PLL were identified to be electrostatic when the lysine residues
Fang Zong et al.
PloS one, 4(10), e7346-e7346 (2009-10-06)
Syndecan-1 forms complexes with growth factors and their cognate receptors in the cell membrane. We have previously reported a tubulin-mediated translocation of syndecan-1 to the nucleus. The transport route and functional significance of nuclear syndecan-1 is still incompletely understood. Here

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