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I2526

Sigma-Aldrich

Insulin-like Growth Factor-II human

≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Sinonimo/i:

IGF-II

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About This Item

Numero MDL:
MFCD00241895
Codice UNSPSC:
12352202
NACRES:
NA.77

Nome del prodotto

Insulin-like Growth Factor-II human, IGF-II, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Origine biologica

human

Livello qualitativo

200

Ricombinante

expressed in E. coli

Saggio

≥98% (SDS-PAGE and HPLC)

Stato

lyophilized powder

Potenza

≤2.0 ng/mL ED50

Qualità

endotoxin tested

PM

7.5 kDa

Confezionamento

pkg of 5X50 μg
pkg of 50 μg

tecniche

cell culture | mammalian: suitable

Impurezze

≤0.1 EU/μg

N° accesso UniProt

P01344

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... IGF2(3481)

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Categorie correlate

Azioni biochim/fisiol

Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth.

Stato fisico

Lyophilized from a 0.2 μm filtered solution with no additives.

Risultati analitici

The biological activity is measured by a cell proliferation assay using mouse FDC-P1

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
SLCL1665
SLCK0806
SLCJ0856
SLCF3014
SLCC7481

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Scientific reports, 7(1), 78-78 (2017-03-03)
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Insulin-like Growth Factors (IGF)

Insulin-like Growth Factors (IGF)

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