I1636
Anti-Human IgM (μ-chain specific) antibody produced in goat
whole antiserum
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About This Item
Prodotti consigliati
Origine biologica
goat
Livello qualitativo
Coniugato
unconjugated
Forma dell’anticorpo
whole antiserum
Tipo di anticorpo
secondary antibodies
Clone
polyclonal
contiene
15 mM sodium azide
tecniche
indirect ELISA: 1:100,000
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
modifica post-traduzionali bersaglio
unmodified
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Descrizione generale
Immunoglobulin M (IgM) is the major component of antibodies. It is the first antibody to be secreted during a primary antibody response, which is expressed in the human fetus. IgM is produced by B1 cells, which is found in blood.
Specificità
The antibody preparation is specific for human IgM when tested against purified human IgA, IgG, Bence Jones Kappa and Bence Jones Lambda light chains
Azioni biochim/fisiol
IgM antibodies are present as pentamers in the serum and are produced in response to antigens.
Immunoglobulin M (IgM) pentamer activates the classical pathway of complement activation and lysis of red blood cells. Monoclonal IgM antibodies provides protection against systemic infection and autoimmune diseases. It does not cross human placenta. IgM regulates B cell development.
Stato fisico
Supplied as a liquid containing 15 mM sodium azide as a preservative.
Stoccaggio e stabilità
For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
nwg
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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Van FR, et al.
The Journal of Experimental Medicine, 122(6), 1173-1188 (1965)
Role of natural and immune IgM antibodies in immune responses
Boes M, et al.
Molecular Immunology, 37(18), 1141-1149 (2000)
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E J Wiersma et al.
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Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
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