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G7879

Sigma-Aldrich

D-Glucose 6-phosphate sodium salt

≥98% (HPLC)

Sinonimo/i:

D(+)-Glucopyranose 6-phosphate sodium salt, G-6-P Na, Robison ester

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About This Item

Formula empirica (notazione di Hill):
C6H12NaO9P
Numero CAS:
54010-71-8
Peso molecolare:
282.12
Beilstein:
5787568
Numero CE:
258-921-0
Numero MDL:
MFCD00006611
Codice UNSPSC:
12352201
ID PubChem:
24895324
NACRES:
NA.25

Origine biologica

synthetic (organic)

Livello qualitativo

300

Saggio

≥98% (HPLC)

Forma fisica

crystalline

tecniche

HPLC: suitable

Colore

white

Intervallo di pH utile

4.0-5.0

Punto di fusione

204 °C (dec.) (lit.)

Solubilità

water: 50 mg/mL, clear, colorless to very faintly yellow

Cationi in tracce

Na: 6.1-10.2% (anhydrous)

Temperatura di conservazione

room temp

Stringa SMILE

[Na+].O[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.Na/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;/h2-10H,1H2,(H2,11,12,13);/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1
ZALKNDISPIVVKC-WYRLRVFGSA-M

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Categorie correlate

Applicazioni

D-glucose-6-phosphate sodium can be used as an energy source for Mycobacterium tuberculosis.

Azioni biochim/fisiol

In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.

Avvertenza

Non-hygroscopic, and very stable to atmospheric moisture at room temperature, unlike the disodium salt.

Altre note

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
There are limited treatment options for enterococcal urinary tract infections, especially vancomycin-resistant Enterococcus (VRE). Oral fosfomycin is a potential option, although limited data are available guiding dosing and susceptibility. We undertook pharmacodynamic profiling of fosfomycin against E. faecalis and E.
Calvin S Carter et al.
Cell metabolism, 32(4), 561-574 (2020-10-08)
Aberrant redox signaling underlies the pathophysiology of many chronic metabolic diseases, including type 2 diabetes (T2D). Methodologies aimed at rebalancing systemic redox homeostasis have had limited success. A noninvasive, sustained approach would enable the long-term control of redox signaling for
Pascal Belin et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(18), 7426-7431 (2009-05-07)
The gene encoding the cytochrome P450 CYP121 is essential for Mycobacterium tuberculosis. However, the CYP121 catalytic activity remains unknown. Here, we show that the cyclodipeptide cyclo(l-Tyr-l-Tyr) (cYY) binds to CYP121, and is efficiently converted into a single major product in
K E Olagaray et al.
PloS one, 14(1), e0210744-e0210744 (2019-01-24)
Systemic inflammation is common in early lactation dairy cows and is associated with decreased milk production. The Scutellaria baicalensis plant contains flavonoids with anti-inflammatory and anti-oxidative properties, which may counteract the inflammatory state in early lactation dairy cows. The objective
Aigi Margus et al.
Journal of economic entomology, 112(5), 2316-2323 (2019-05-14)
Organisms live in complex multivariate environments. In agroecosystems, this complexity is often human-induced as pest individuals can be exposed to many xenobiotics simultaneously. Predicting the effects of multiple stressors can be problematic, as two or more stressors can have interactive
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Articoli

Nucleotide Synthesis in Cancer Cells

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA.

Insulin Signaling and Energy Homeostasis

Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.

Aerobic Glycolysis and the Warburg Effect

We presents an article about the Warburg effect, and how it is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer cells show an increased dependence on glycolysis to meet their energy needs, regardless of whether they were well-oxygenated or not.

Protocolli

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

Enzymatic Assay of Glucose-6-Phosphate Dehydrogenase (EC 1.1.1.49)

Enzymatic Assay of Glucose-6-Phosphate Dehydrogenase (EC 1.1.1.49)

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