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Merck
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Key Documents

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G3127

Sigma-Aldrich

Gly-Sar

≥98% (TLC)

Sinonimo/i:

Glycyl-sarcosine

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About This Item

Formula condensata:
NH2CH2CON(CH3)CH2COOH
Numero CAS:
29816-01-1
Peso molecolare:
146.14
Beilstein:
1768450
Numero CE:
249-875-2
Numero MDL:
MFCD00038193
Codice UNSPSC:
12352209
ID PubChem:
24895113
NACRES:
NA.26

product name

Gly-Sar,

Saggio

≥98% (TLC)

Forma fisica

powder

Colore

white

Punto di fusione

198 °C

Temperatura di conservazione

−20°C

Stringa SMILE

CN(CC(O)=O)C(=O)CN

InChI

1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)
VYAMLSCELQQRAE-UHFFFAOYSA-N

Informazioni sul gene

human ... SLC15A1(6564)

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Hovhannes J Gukasyan et al.
Pharmaceutical research, 34(12), 2488-2497 (2017-08-24)
Studies were conducted in primary cultured rat alveolar epithelial cell monolayers to characterize peptide transporter expression and function. Freshly isolated rat lung alveolar epithelial cells were purified and cultured on permeable support with and without keratinocyte growth factor (KGF). Messenger
Jinling Wang et al.
International journal of nanomedicine, 13, 7997-8012 (2018-12-13)
Polymeric micelles (PMs) hold promise for improving solubility and oral absorption of poorly soluble drugs. Unfortunately, the oral absorption of PMs is also limited by intestinal epithelium. To improve the oral delivery efficiency of micelles, transporter-mediated micelles could enhance the
Dilara Jappar et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(10), 1740-1746 (2010-07-28)
The purpose of this study was to evaluate the role, relevance, and regional dependence of peptide transporter (PEPT) 1 expression and function in mouse intestines using the model dipeptide glycylsarcosine (GlySar). After isolating specific intestinal segments, in situ single-pass perfusions
Yuhuan Chen et al.
Journal of agricultural and food chemistry, 67(30), 8370-8381 (2019-07-05)
Naturally occurring dietary peptides derived from gastrointestinal digestates of common bean milk and yogurt were studied for their bioaccessibility, bioavailability, and anti-inflammatory activity in both Caco-2 mono- and Caco-2/EA.hy926 co-culture cell models. Anti-inflammatory activities of these peptide extracts were found
Jian Cang et al.
Drug metabolism and pharmacokinetics, 25(5), 500-507 (2010-09-30)
To investigate the pharmacokinetics and mechanism of intestinal absorption of JBP485 in rats, the pharmacokinetics of JBP485 were investigated in vivo both intravenously and orally. The effects of glycylsarcosine (Gly-Sar) on the uptake and transepithelial transport of JBP485 were examined
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