Passa al contenuto
Merck
Tutte le immagini(3)

Key Documents

Altri documenti

F9677

Sigma-Aldrich

Felodipine

solid

Sinonimo/i:

4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester, Plendil

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(3)

About This Item

Formula empirica (notazione di Hill):
C18H19NO4Cl2
Numero CAS:
72509-76-3
Peso molecolare:
384.25
Numero MDL:
MFCD00868316
Codice UNSPSC:
12352200
ID PubChem:
24278449

Forma fisica

solid

Livello qualitativo

200

Solubilità

DMSO: 20 mg/mL
H2O: insoluble

Ideatore

AstraZeneca

Stringa SMILE

CCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(Cl)c2Cl)C(=O)OC

InChI

1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
RZTAMFZIAATZDJ-UHFFFAOYSA-N

Informazioni sul gene

human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779) , CACNA2D1(781) , NR3C2(4306)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Felodipine is a dihydropyridine derivative. It has diuretic properties. Felodipine has high vascular selectivity. It is used to treat hypertension. Felodipine regulates chronic stable angina.

Azioni biochim/fisiol

L-type calcium channel blocker

Caratteristiche e vantaggi

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Avvertenze

Warning

Indicazioni di pericolo

H302 - H361d - H373 - H410

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Inhalation

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 9

1 of 9

Sigma-Aldrich

Sigma-Aldrich

SML0946

Lacidipine

Nicardipine hydrochloride powder, ≥98%

Sigma-Aldrich

N7510

Nicardipine hydrochloride

Amlodipine besylate ≥98% (HPLC)

Sigma-Aldrich

A5605

Amlodipine besylate

Sarafloxacin hydrochloride hydrate VETRANAL®, analytical standard

Supelco

33497

Sarafloxacin hydrochloride hydrate

Benidipine hydrochloride ≥98% (HPLC)

Sigma-Aldrich

B6813

Benidipine hydrochloride

Nimodipine

Sigma-Aldrich

N149

Nimodipine

Nisoldipine ≥98% (HPLC)

Sigma-Aldrich

N0165

Nisoldipine

Nifedipine ≥98% (HPLC), powder

Sigma-Aldrich

N7634

Nifedipine

R(+)-IAA-94 ≥98% (HPLC), solid

Sigma-Aldrich

I117

R(+)-IAA-94

Haiyan Li et al.
International journal of pharmaceutics, 427(2), 270-275 (2012-03-01)
Tomographic imaging techniques are attractive tools for the visualization of the internal structural characteristics of pharmaceutical solid dosage forms. In this paper, the internal structure of the tablet core for a monolith osmotic drug delivery system, felodipine sustained-release tablet, was
Marianne Dybdahl et al.
Toxicology and applied pharmacology, 262(3), 301-309 (2012-05-26)
The pregnane X receptor (PXR) has a key role in regulating the metabolism and transport of structurally diverse endogenous and exogenous compounds. Activation of PXR has the potential to initiate adverse effects, causing drug-drug interactions, and perturbing normal physiological functions.
Nikolaos Scoutaris et al.
Journal of materials science. Materials in medicine, 23(2), 385-391 (2011-11-16)
Three different formulations comprising two drugs, felodipine and hydrochlorothiazide (HCT) and two polymers, poly(vinyl pyrolidone) (PVP) and poly(lactic-co-glycolic acid) (PLGA) were inkjet printed as micro-dot arrays and analysed on an individual micro-spot basis by time-of-flight secondary ion mass spectrometry (ToF-SIMS).
Emilie Hénin et al.
The AAPS journal, 14(2), 155-163 (2012-01-31)
Absorption models used in the estimation of pharmacokinetic drug characteristics from plasma concentration data are generally empirical and simple, utilizing no prior information on gastro-intestinal (GI) transit patterns. Our aim was to develop and evaluate an estimation strategy based on
Yuqing Zhang et al.
Journal of hypertension, 30(11), 2202-2212 (2012-09-20)
In antihypertensive treatment trials, when randomized therapies do not reach target, additional drugs are administered. However, patients requiring (add-on) or not requiring add-on therapy (no-add-on) may be at different cardiovascular risk and differently susceptible to benefits of antihypertensive treatment. The
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.