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Key Documents

F8384

Sigma-Aldrich

Flavin adenine dinucleotide disodium salt hydrate

BioReagent, suitable for cell culture

Sinonimo/i:

FAD, FAD-Na2, Riboflavin 5′-adenosine diphosphate disodium salt

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About This Item

Formula empirica (notazione di Hill):
C27H31N9Na2O15P2 · xH2O
Numero CAS:
Peso molecolare:
829.51 (anhydrous basis)
Beilstein:
5326842
Numero MDL:
Codice UNSPSC:
12352207
ID PubChem:
NACRES:
NA.75

Origine biologica

bovine milk

Livello qualitativo

Nome Commerciale

BioReagent

Saggio

≥95%

Forma fisica

powder

tecniche

cell culture | mammalian: suitable

Solubilità

water: 50 mg/mL, clear

Temperatura di conservazione

−20°C

Stringa SMILE

[Na+].[Na+].[H]O[H].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP([O-])(=O)OP([O-])(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)n5cnc6c(N)ncnc56)c2cc1C

InChI

1S/C27H33N9O15P2.2Na.H2O/c1-10-3-12-13(4-11(10)2)35(24-18(32-12)25(42)34-27(43)33-24)5-14(37)19(39)15(38)6-48-52(44,45)51-53(46,47)49-7-16-20(40)21(41)26(50-16)36-9-31-17-22(28)29-8-30-23(17)36;;;/h3-4,8-9,14-16,19-21,26,37-41H,5-7H2,1-2H3,(H,44,45)(H,46,47)(H2,28,29,30)(H,34,42,43);;;1H2/q;2*+1;/p-2/t14-,15+,16+,19-,20+,21+,26+;;;/m0.../s1
GXTPHHZYFMAGLX-UJXBNFGUSA-L

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Descrizione generale

Flavin adenine dinucleotide (FAD) is a redox cofactor of flavoproteins, such as cytochrome-b5 reductase enzyme. With the help of nicotinamide adenine dinucleotide phosphate (NADPH), FAD can be reduced to form FADH2.

Applicazioni

Flavin adenine dinucleotide (FAD) is used as a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. FAD is a component of the pyruvate dehydrogenase complex.
Flavin adenine dinucleotide disodium salt hydrate has been used as a component in the extraction buffer for plant tissue extraction. It has also been used to study its effects on infarct areas of middle cerebral artery occlusion (MCAO) induced mice.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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