Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

D6035

Sigma-Aldrich

Disopyramide phosphate salt

Sinonimo/i:

α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula condensata:
C21H29N3O · H3PO4
Numero CAS:
22059-60-5
Peso molecolare:
437.47
Numero CE:
244-756-1
Numero MDL:
MFCD00069254
Codice UNSPSC:
12352200
ID PubChem:
24277706
NACRES:
NA.77

Stato

solid

Livello qualitativo

200

Stringa SMILE

OP(O)(O)=O.CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C

InChI

1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2,3,4)
CGDDQFMPGMYYQP-UHFFFAOYSA-N

Informazioni sul gene

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Categorie correlate

Applicazioni

Disopyramide phosphate salt has been used as an internal standard for plasma sample analysis by mass spectrometry. It might be used as a test compound in a teratogenicity study.

Azioni biochim/fisiol

Class IA antiarrhythmic; sodium channel blocker
Disopyramide is found to stabilize the cell membrane by altering the action potential. It might act as an antiarrhythmic agent.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
018F0560

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 8

1 of 8

Quinidine hydrochloride monohydrate technical grade

Sigma-Aldrich

Q0750

Quinidine hydrochloride monohydrate

Clarithromycin ≥95% (HPLC)

Sigma-Aldrich

C9742

Clarithromycin

Chlorpromazine hydrochloride ≥98% (TLC)

Sigma-Aldrich

C8138

Chlorpromazine hydrochloride

Lidocaine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1034

Lidocaine

5-Fluorocytosine nucleoside analog

Sigma-Aldrich

F7129

5-Fluorocytosine

Itraconazole ≥98% (HPLC)

Sigma-Aldrich

I6657

Itraconazole

Quinidine anhydrous

Sigma-Aldrich

Q3625

Quinidine

Lidocaine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1257

Lidocaine hydrochloride

0
Drugs for Pregnant and Lactating Women, 252-338 (2009)
Anthony A Fossa et al.
The Journal of pharmacology and experimental therapeutics, 302(2), 828-833 (2002-07-20)
QT interval prolongation of the electrocardiogram has been associated with the occurrence of life-threatening fatal ventricular arrhythmias. To understand the relationship between preclinical cardiac conduction assessment to clinical outcome, comparisons of free (unbound)-plasma drug concentrations and their associated effects in
Shunichiro Sumi et al.
Pacing and clinical electrophysiology : PACE, 33(6), e53-e56 (2010-01-12)
The patient was a 57-year-old man with Brugada syndrome, who had been implanted with a implantable cardioverter defibrillator (ICD). The frequency of ventricular fibrillation (VF) started to increase about 4 years after ICD implantation, occurring, at worst, six times in
Annerie M E Moers et al.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 14(3), 426-430 (2011-09-22)
Patients undergo ablation for focal atrial fibrillation (AF) as a result of failure of anti-arrhythmic drugs. Our basic studies have implicated cholinergic and adrenergic neurotransmitter release as the underlying mechanism for focal AF. Therefore, we tested the efficacy of a
Aziza El Harchi et al.
Journal of molecular and cellular cardiology, 52(1), 185-195 (2011-10-13)
The Class Ia antiarrhythmic drug disopyramide (DISO) causes QT interval prolongation that is potentially dangerous in acquired Long QT Syndrome but beneficial in short QT syndrome, through inhibition of the hERG-encoded channels responsible for rapid delayed rectifier K(+) current (I(Kr)).
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.