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C3809

Sigma-Aldrich

Ceftazidime hydrate

90.0-105.0%, contains ~10% sodium carbonate as stabilizer

Sinonimo/i:

1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinum

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About This Item

Formula empirica (notazione di Hill):
C22H22N6O7S2 · xH2O
Numero CAS:
120618-65-7
Peso molecolare:
546.58 (anhydrous basis)
Numero MDL:
MFCD00153936
Codice UNSPSC:
51284108
ID PubChem:
24892644
NACRES:
NA.85

Livello qualitativo

200

Saggio

90.0-105.0%

Forma fisica

powder or crystals

contiene

~10% sodium carbonate as stabilizer

Spettro attività antibiotica

Gram-negative bacteria
Gram-positive bacteria

Modalità d’azione

cell wall synthesis | interferes

Temperatura di conservazione

2-8°C

Stringa SMILE

[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].CC(C)(O\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3ccccc3)=C(N2C1=O)C([O-])=O)c4csc(N)n4)C(O)=O

InChI

1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13-;;;;;/t14-,18-;;;;;/m1...../s1
NMVPEQXCMGEDNH-TZVUEUGBSA-N

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Descrizione generale

Broad spectrum antibiotic; third generation cephalosporin
Chemical structure: ß-lactam

Applicazioni

Ceftazidime hydrate is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis. It is also used in bacterial susceptibility studies and to select mutant colonies of interest.

Azioni biochim/fisiol

Cephalosporins, such as ceftazidime , disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.

Altre note

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H317,H319,H334

Classi di pericolo

Eye Irrit. 2 - Resp. Sens. 1 - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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