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Merck
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Key Documents

B2643

Sigma-Aldrich

Estere N-idrossisuccinimmidico dell′acido biotinammidoesanoico

≥98% (TLC), powder

Sinonimo/i:

(+)-Biotinammidocaproato di N-succinimmidile, 6-(biotinammido)esanoato di succinimmidile, Estere N-succinimmidilico dell’acido N-(+)-biotinil-6-amminocaproico, Estere NHS dell'acido N-(+)-biotinil-6-amminoesanoico, N-biotinil-6-amminocaproato di N-succinimmidile

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About This Item

Formula empirica (notazione di Hill):
C20H30N4O6S
Numero CAS:
Peso molecolare:
454.54
Beilstein:
3577403
Numero MDL:
Codice UNSPSC:
12352203
ID PubChem:
NACRES:
NA.46

Livello qualitativo

Saggio

≥98% (TLC)

Forma fisica

powder

Solubilità

H2O: ≤2 mg/mL (with sonication)
DMF: 50 mg/mL (Stable up to 2 months in dry DMF.)

Temperatura di conservazione

−20°C

Stringa SMILE

[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2

InChI

1S/C20H30N4O6S/c25-15(7-4-3-6-14-19-13(12-31-14)22-20(29)23-19)21-11-5-1-2-8-18(28)30-24-16(26)9-10-17(24)27/h13-14,19H,1-12H2,(H,21,25)(H2,22,23,29)/t13-,14-,19-/m0/s1
UVGHPGOONBRLCX-NJSLBKSFSA-N

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Applicazioni

Biotinamidohexanoic acid N-hydroxysuccinimide ester has been used in the biotinylation of antibodies.

Azioni biochim/fisiol

Biotin is a label widely used in several biochemical applications and has a high affinity for avidin. A spacer chain is required to reduce steric hindrance while coupling biotin (a small molecule) to biopolymers (large molecules). Biotinamidohexanoic acid N-hydroxysuccinimide ester incorporates a 7-atom spacer with the N-succinimide leaving group. It can react with a primary amine in the pH range of 6.5-8.5. This biotinylation reagent incorporates an aminocaproyl spacer and thus can reduce the steric hindrance in binding avidin to some biotinylated compounds.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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