Passa al contenuto
Merck
Tutte le immagini(1)

Key Documents

View All Documentation

A7755

Sigma-Aldrich

5α-Androstane-3α,17β-diol

Sinonimo/i:

3α,17β-Dihydroxy-5α-androstane, Dihydroandrosterone

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula empirica (notazione di Hill):
C19H32O2
Numero CAS:
1852-53-5
Peso molecolare:
292.46
Numero CE:
217-447-4
Numero MDL:
MFCD00003676
Codice UNSPSC:
51111800
ID PubChem:
24278236
NACRES:
NA.77

Saggio

≥98% (TLC)

Livello qualitativo

200

Forma fisica

powder

Controllo stupefacenti

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

tecniche

toxicology assay: suitable

Solubilità

methanol: 19.60-20.40 mg/mL, clear, colorless

Temperatura di conservazione

room temp

Stringa SMILE

[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C19H32O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-17,20-21H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,17-,18-,19-/m0/s1
CBMYJHIOYJEBSB-KHOSGYARSA-N

Informazioni sul gene

rat ... Ar(24208)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Applicazioni

5α-Androstane-3α,17β-diol (dihydroandrosterone) is a testosterone metabolite. Dihyroandrosterone inhibited the cell growth of seven cancer cell lines while showing weak toxicity on normal cell lines.

Azioni biochim/fisiol

Dihydroandrosterone is a testosterone metabolite; affects sperm maturation and survival.

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H351,H360FD

Consigli di prudenza

P201 - P308 + P313

Classi di pericolo

Carc. 2 - Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Wei Liu et al.
Journal of chromatography. A, 1233, 1-7 (2012-03-06)
In this paper, a convenient and self-assembled hollow fiber solvent-stir bar microextraction (HF-SSBME) device was developed, which could stir by itself. In the extraction process, the proposed device made the solvent "bar" not floating at the sample solution and exposing
Hajer Jegham et al.
Anti-cancer drugs, 23(8), 803-814 (2012-03-01)
This study investigated the antineoplasic potential of a new family of aminosteroids. The antiproliferative activity of seven 5α-androstane-3α,17β-diol derivatives selected from a screening study was measured on nine cancerous cell lines (HL-60, K-562, LNCaP, PC-3, Shionogi, MCF-7, MDA-MB-231, BT-20, and
J P Deslypere et al.
The Journal of clinical endocrinology and metabolism, 53(2), 430-434 (1981-08-01)
Testosterone, 5 alpha-androstane-17 beta-ol-3-one (DHT) and 5 alpha-androstane-3 alpha,17 beta-diol (Adiol) concentrations were measured in postmortem tissues (pubic skin, scrotal skin, thigh skin, and striated muscle) from 24 males, aged 20-82 yr. Androgen concentrations were highest in scrotal skin, followed
Cheryl A Frye
Pharmacology, biochemistry, and behavior, 86(2), 354-367 (2006-11-23)
The abuse of anabolic-androgenic steroids (AS) is a growing problem; however, the effects and mechanisms underlying their addictive effects are not well understood. Research findings regarding androgen abuse in people and hedonic effects of androgens in laboratory rats are reviewed.
D H Garnier et al.
General and comparative endocrinology, 116(2), 281-290 (1999-11-24)
Concentrations of testosterone, progesterone, Delta4-androstenedione, dihydrotestosterone, 11-ketotestosterone, estrone, estradiol-17beta, 5alpha-androstane, 3alpha, 17beta-diol, and 17alpha-hydroxy, 20beta-dihydroprogesterone were determined by radioimmunoassays in the blood plasma and testicular homogenates of Scyliorhinus canicula. Samples were collected almost every month for 27 months. The weights
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.