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Merck
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Documenti fondamentali

A6412

Sigma-Aldrich

Aflatoxin M1–BSA Conjugate

Sinonimo/i:

AFM1-BSA conjugate

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About This Item

Numero MDL:
MFCD00130364
Codice UNSPSC:
12352200
NACRES:
NA.77

Stato

powder

Livello qualitativo

200

Grado di funzionalizzazione

4-8 mol aflatoxin M1 per mol BSA (Lowry)

Temperatura di conservazione

2-8°C

Descrizione generale

Aflatoxin M1 is a hydroxylated metabolite ofaflatoxin B1. It is found in milk secreted by mammary glands of lactatinganimals, humans, and milk products.

Applicazioni

Aflatoxin M1–BSA Conjugate has been used in the indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) with non-labeled aflatoxin M1 and anti-AFM1 antibody.

Azioni biochim/fisiol

Aflatoxin M1 is a mycotoxin that elicits both hepatotoxic and hepatocarcinogenic effects leading to immunosuppression in animals. The bioconjugate of aflatoxin M1 (AFM1) with bovine serum albumin (BSA) is useful in the generation of AFM1 specific antibodies which may have immunoassay applications.

Attenzione

Possibly carcinogenic.

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H300 + H310 + H330,H350

Classi di pericolo

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
075M4024V
028M4073V
039M4003V
14181203
128M4153V

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Fatemeh Khademi et al.
Jundishapur journal of microbiology, 8(4), e16850-e16850 (2015-06-03)
Aflatoxins are the most extensively studied group of mycotoxins produced by molds, especially the Aspergillus group, which are highly toxic to animals and humans. Since immunoassay is a simple and rapid method for the analysis of many toxic substances in
K Thirumala-Devi et al.
Journal of agricultural and food chemistry, 50(4), 933-937 (2002-02-07)
High-titer rabbit polyclonal antibodies to aflatoxin M(1) (AFM1) were produced by utilizing AFM1-bovine serum albumin (BSA) conjugate as an immunogen. An indirect competitive enzyme-linked immunosorbent assay was standardized for estimating AFM1 in milk and milk products. To avoid the influence
A Radoi et al.
Talanta, 77(1), 138-143 (2008-09-23)
Five different clones of antibodies developed against the aflatoxin M(1) were investigated by using the classical indirect and direct competitive Enzyme-Linked Immunosorbent Assay (ELISA) formats, and also the direct competitive ELISA based on the use of the superparamagnetic nanoparticles. The

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