A8679

Anti-Aflatoxin B₁ antibody produced in rabbit

fractionated antiserum, buffered aqueous solution

• Sinonimo/i: Anti-Aflatoxin B₁
• Codice UNSPSC: 12352203
• NACRES: NA.46

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 200
• Coniugato: unconjugated
• Forma dell’anticorpo: fractionated antiserum
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• tecniche: capture ELISA: 1:4,000 using aflatoxin B₁-BSA
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified

Descrizione

Descrizione generale

Aflatoxin B₁ is the most abundant and significant member of the group, which includes B₂, B_2a, G₁, G_2a, M₁, M₂, P₁, Q1, aflatoxicol I (natural isomer), aflatoxicol II (unnatural isomer), tetrahydrodeoxy aflatoxin B1, and the unstable reactive B₁ (8,9)-epoxide.

Aflatoxins are highly carcinogenic.

Aflatoxins are highly toxic mycotoxins produced by the fungus Aspergillus. Aflatoxins are commonly found in various grains and peanut butter.

Mycotoxins, a group of chemically diverse secondary fungal metabolites, induce a variety of toxic responses in humans and animals when food and feed containing these compounds are ingested. Rapidly quantitating levels of mycotoxin contamination can help reduce exposure to these toxins.

The antibody reacts with the B₁ aflatoxin and also recognizes aflatoxins G₁, B₂, and the KLH protein. No cross-reaction is observed with aflatoxins and B_2a, G₂, G_2a, M₁.

Specificità

Sensitivity range for this product is 0.005-20 ng/ml of aflatoxin B₁.

Immunogeno

aflatoxin B₁-KLH.

Applicazioni

Rabbit Anti-Aflatoxin B1 antibody has been used for the development of electrochemical immunosensors. The antibody has also been used in designing novel sandwich immunoassays. The product can also be used for capture ELISA at a dilution of 1:1,000.

Azioni biochim/fisiol

Aflatoxin B₁ and its metabolites act as potent carcinogens, mutagens and teratogens. Aflatoxins have been implicated in human hepatocellular carcinoma, outbreaks of aflatoxicosis, Rey′s syndrome, chronic hepatitis and increased mortality from infection in animal husbandry.

Stato fisico

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable