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Documenti fondamentali

A3759

Sigma-Aldrich

p-Aminohippuric acid sodium salt

Sinonimo/i:

N-(p-Aminobenzoyl)glycine

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About This Item

Formula condensata:
C9H9N2O3Na
Numero CAS:
Peso molecolare:
216.17
Numero CE:
Numero MDL:
Codice UNSPSC:
12352106
ID PubChem:
NACRES:
NA.26

Saggio

≥98% (TLC)

Stato

powder

Colore

white to off-white

applicazioni

cell analysis

Stringa SMILE

[Na].Nc1ccc(cc1)C(=O)NCC(O)=O

InChI

1S/C9H10N2O3.Na.H/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13;;/h1-4H,5,10H2,(H,11,14)(H,12,13);;
IGACXVXMVJUFOL-UHFFFAOYSA-N

Azioni biochim/fisiol

Para-Aminohippuric acid (PAH), OAT-1 specific, is used to help differentiate and characterized organic anion transporter (OAT) isoforms.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Uric acid ≥99%, crystalline

Sigma-Aldrich

U2625

Uric acid

Chiao-Shih Tseng et al.
Advances in pharmacological sciences, 2011, 204501-204501 (2011-07-09)
The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli. To investigate the effects of AA on renal functions and the pharmacokinetics (PKs) of p-aminohippuric acid (PAH) and
Chi Chun Wong et al.
Biochemical pharmacology, 81(7), 942-949 (2011-01-20)
Flavonoids are conjugated by phase II enzymes in humans to form glucuronidated and sulfated metabolites that are excreted in urine via the kidney. In this study, we examined the interaction between metabolites of quercetin and isoflavonoids found in vivo with
Nadiya Bakhiya et al.
Toxicology, 264(1-2), 74-79 (2009-08-01)
Aristolochic acid (AA), present in Aristolochia species, is the major causative agent in the development of severe renal failure and urothelial cancers in patients with AA nephropathy. It may also be a cause of Balkan endemic nephropathy. Epithelial cells of
M M Al-Bataineh et al.
Journal of veterinary pharmacology and therapeutics, 35(3), 209-215 (2011-06-01)
Mammary epithelial cells express a diversity of membrane transporters including members of organic cation and organic anion (OAT) transporter subfamilies. Four mammal OAT isoforms have been identified: OAT-1, OAT-2, OAT-3, and OAT-4. The pharmacological significance of OAT isoforms has been
Andrew A Udy et al.
Critical care (London, England), 18(6), 657-657 (2014-11-30)
The aim of this study was to explore changes in glomerular filtration (GFR) and renal tubular function in critically ill patients at risk of augmented renal clearance (ARC), using exogenous marker compounds. This prospective, observational pharmacokinetic (PK) study was performed

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