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Documenti fondamentali

A3253

Sigma-Aldrich

Ala-Pro hydrate

≥98% (TLC), suitable for ligand binding assays

Sinonimo/i:

L-Alanyl-L-proline hydrate

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About This Item

Formula empirica (notazione di Hill):
C8H14N2O3 · xH2O
Numero CAS:
Peso molecolare:
186.21 (anhydrous basis)
Beilstein:
3546017
Numero CE:
Numero MDL:
Codice UNSPSC:
12352202
ID PubChem:
NACRES:
NA.26

Nome del prodotto

Ala-Pro hydrate,

Saggio

≥98% (TLC)

Stato

powder

tecniche

ligand binding assay: suitable

Colore

white to off-white

Temperatura di conservazione

−20°C

Stringa SMILE

O.C[C@H](N)C(=O)N1CCC[C@H]1C(O)=O

InChI

1S/C8H14N2O3.H2O/c1-5(9)7(11)10-4-2-3-6(10)8(12)13;/h5-6H,2-4,9H2,1H3,(H,12,13);1H2/t5-,6-;/m0./s1
SSUWZOPYGFOQJA-GEMLJDPKSA-N

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Azioni biochim/fisiol

Alanyl dipeptides such as ala-leu, ala-lys, ala-gly, ala-pro, ala-tyr and ala-phe may be used in physicochemical studies or to evaluate dipeptide separation technologies. Alanyl dipeptides may also be used for studying cell uptake mechanisms, dipeptide metabolism or cell growth supplementation benefits.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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H Ke et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(8), 3324-3328 (1993-04-15)
Cyclophilin is a binding protein for the immunosuppressive drug cyclosporin A and is also an enzyme with peptidyl-prolyl cis-trans isomerase activity. The crystal structure of cyclophilin A complexed with the substrate Ala-Pro has been determined and refined to an R
R Hanai et al.
Journal of chromatography, 394(2), 273-278 (1987-05-22)
The "elution-band relaxation method" has been applied to the analysis of the cis-trans kinetics isomerization of the proline of L-Ala-L-Pro using reversed-phase liquid chromatography. A procedure suitable for cases where neither isomer can be injected separately is described.
Yan Chen et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 22(1), 9-14 (2006-01-25)
A micro-reactor system with continual spectrophotometric detection has been operated in Sequential Injection lab-on-valve (SI-LOV) mode and applied to enzyme kinetics and inhibition studies, using acetylcholinesterase (AChE) and angiotensin-converting enzyme (ACE) as model systems. With the advantages of automation, real-time
Byung Jin Byun et al.
The journal of physical chemistry. B, 114(44), 14077-14086 (2010-10-19)
Conformational preferences and prolyl cis-trans isomerizations of the X-Pro motifs (Ac-X-Pro-NHMe, X = Ala and Aib) are explored using the meta-hybrid functional M06-2X and the double-hybrid functional B2PLYP-D with empirical dispersion corrections in the gas phase and in water, where
Young-Ok Kim et al.
The Journal of general and applied microbiology, 55(5), 345-350 (2009-11-27)
Citrobacter braakii produced an intracellular acid glucose phosphatase (AgpC) which was purified 986 fold to homogeneity with the specific activity of 286 units/mg. AgpC hydrolyzed a wide variety of phosphorylated compounds with high activity for glucose-1-phosphate and glucose-6-phosphate. The optimum

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