85578

Spermidine trihydrochloride

BioXtra, ≥99.5% (AT)

• Sinonimo/i: N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
• Formula condensata: NH₂(CH₂)₃NH(CH₂)₄NH₂ · 3HCl
• Numero CAS: 334-50-9
• Peso molecolare: 254.63
• Beilstein: 3552356
• Numero CE: 206-379-0
• Numero MDL: MFCD00012918
• Codice UNSPSC: 12352116
• ID PubChem: 57653005
• NACRES: NA.26

Proprietà

• Nome Commerciale: BioXtra
• Livello qualitativo: 100
• Saggio: ≥99.0% (TLC); ≥99.5% (AT)
• Forma fisica: powder
• Impurezze: insoluble matter, passes filter test
• pH: 3.0-6.0 (25 °C, 1 M in H₂O)
• Punto di fusione: 257-259 °C (lit.)
• Solubilità: H₂O: 1 M at 20 °C, clear, colorless
• Anioni in tracce: sulfate (SO₄^2-): ≤50 mg/kg
• Cationi in tracce: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤10 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Assorbanza UV: λ: 260 nm A_max: 0.2; λ: 280 nm A_max: 0.1
• Stringa SMILE: Cl[H].Cl[H].Cl[H].NCCCCNCCCN
• InChI: 1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H; LCNBIHVSOPXFMR-UHFFFAOYSA-N

Descrizione

Descrizione generale

Spermidine trihydrochloride is an aliphatic polyamine. Its crystalline structure has been studied. It has been reported to preserve the nuclei and prevent proteolytic degradation of histones during the macronuclei isolation from Tetrahymena pyriformis.

Applicazioni

Spermidine trihydrochloride is used for the following applications:

• DNA extraction and restriction endonuclease digestion
• Nuclear transplantation
• During the chemical analyses of the squid species Todaropsis eblanae
• As one of the agents in intercalating drug.
• Platelet aggregation

It may be used in the synthesis of palladium complexes like [sperH₃]₂[PdCl₄]₃, [PdCl₂(sperH)]₂[PdCl₄], and [(PdCl₂)₃(sper)₂] by reacting with K₂PdCl₄ and PdCl₂.

Azioni biochim/fisiol

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Avvertenza

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Altre note

Buffer component for chromosome isolation in bivariate flow cytogenetic analysis and sorting.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319
• Consigli di prudenza: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves