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76532

Sigma-Aldrich

Geranyl pyrophosphate lithium salt

≥95.0% (TLC)

Sinonimo/i:

(E)-3,7-Dimethyl-2,6-octadien-1-ol trihydrogen pyrophosphate lithium salt, (E)-3,7-Dimethyl-2,6-octadien-1-yl pyrophosphate lithium salt, GPP-Li

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About This Item

Formula empirica (notazione di Hill):
C10H20O7P2 · xLi+
Numero CAS:
21141-43-5
Peso molecolare:
314.21 (free acid basis)
Beilstein:
1915690
Codice UNSPSC:
85151701
NACRES:
NA.25

Livello qualitativo

100

Saggio

≥95.0% (TLC)

Forma fisica

powder

Temperatura di conservazione

−20°C

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Categorie correlate

Azioni biochim/fisiol

Metabolite in monoterpenoid biosynthesis, substrate for monoterpene synthases.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Joris W De Schutter et al.
Bioorganic & medicinal chemistry letters, 20(19), 5781-5786 (2010-08-31)
A structure-based approach was pursued in designing novel bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase (hFPPS). Preliminary SAR and structural evidence for the simultaneous binding of these inhibitors into the isopentenyl pyrophosphate (IPP) and the geranyl pyrophosphate (GPP) substrate
Fu-Lien Hsieh et al.
Journal of molecular biology, 404(5), 859-873 (2010-10-23)
Isoprenoids, most of them synthesized by prenyltransferases (PTSs), are a class of important biologically active compounds with diverse functions. The mint geranyl pyrophosphate synthase (GPPS) is a heterotetramer composed of two LSU·SSU (large/small subunit) dimers. In addition to C(10)-GPP, the
J Fraser Glickman et al.
Assay and drug development technologies, 5(2), 205-214 (2007-05-05)
A mix-and-read FlashPlate (PerkinElmer, Waltham, MA) assay for the enzyme farnesyl pyrophosphate (FPP) synthase (FPPS) was developed to rapidly measure both steps in the synthesis of FPP from dimethylallyl pyrophosphate (DMAPP). The assay used either DMAPP or geranyl pyrophosphate (GPP)
Tao-Hsin Chang et al.
The Plant cell, 22(2), 454-467 (2010-02-09)
Terpenes (isoprenoids), derived from isoprenyl pyrophosphates, are versatile natural compounds that act as metabolism mediators, plant volatiles, and ecological communicators. Divergent evolution of homomeric prenyltransferases (PTSs) has allowed PTSs to optimize their active-site pockets to achieve catalytic fidelity and diversity.
Kuan-Hung Chen et al.
The Journal of organic chemistry, 74(2), 895-898 (2008-12-04)
Hexaamide receptor 4 and coumarin phosphate 5 form an ensemble for effective sensing of geranyl pyrophosphate (GPP). Fluorescence resonance energy transfer in the 4 + 5 ensemble diminishes when 5 is replaced by GPP. Receptor 4 binds selectively with GPP
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