75351

Oligomycin A

≥99% (HPLC)

• Sinonimo/i: MCH 32
• Formula empirica (notazione di Hill): C₄₅H₇₄O₁₁
• Numero CAS: 579-13-5
• Peso molecolare: 791.06
• Beilstein: 5702132
• Numero CE: 209-437-3
• Numero MDL: MFCD00065705
• Codice UNSPSC: 51102829
• ID PubChem: 57652563
• NACRES: NA.76

Proprietà

• Saggio: ≥99% (HPLC)
• Forma fisica: powder
• Colore: white to off-white
• Solubilità: DMSO: soluble
• Spettro attività antibiotica: fungi
• Modalità d’azione: enzyme | inhibits
• Temperatura di conservazione: −20°C
• Stringa SMILE: CCC1CCC2OC3(CC[C@@H](C)C(C[C@H](C)O)O3)[C@H](C)C(OC(=O)\C=C\[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C\1)[C@H]2C
• InChI: 1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15+,21-18+/t25-,26-,27+,28+,29+,30-,31+,32+,33-,34?,35?,36?,38+,40-,41?,42-,44+,45?/m1/s1; MNULEGDCPYONBU-VVXVDZGXSA-N

Descrizione

Descrizione generale

Chemical structure: macrolide

Applicazioni

Oligomycin was used to inhibit sucrose synthesis and ¹⁴C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O₂ and CO₂ in the cat. Inhibits the growth of Rhodotorula glutinis, Aspergillus niger and other molds.

Azioni biochim/fisiol

Oligomycin blocks oxidative phosphorylation and the electron transport chain by inhibiting membrane bound mitochondrial ATP synthase (ATPase) and proton channel (pump, FO subunit) blocker.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves