468R-1

Claudin-4 (EP417) Rabbit Monoclonal Primary Antibody

• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: EP417, monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (468R-14); vial of 0.1 mL concentrate Research Use Only (468R-14-RUO); vial of 0.5 mL concentrate (468R-15); vial of 1.0 mL concentrate (468R-16); vial of 1.0 mL concentrate Research Use Only (468R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (468R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (468R-17); vial of 7.0 mL pre-dilute ready-to-use (468R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (468R-18-RUO)
• Produttore/marchio commerciale: Cell Marque^™
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 (concentrated)
• Isotipo: IgG
• Controllo: lung adenocarcinoma
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: membranous
• Informazioni sul gene: human ... CLDN4(1364)

Descrizione

Descrizione generale

The claudin-family proteins are a group of tight-junction membranous proteins responsible for paracellular molecular flow between adjacent cells of the epithelium.¹ In normal kidney, claudin-4 plays a key role in paracellular ion reabsorption.² Claudin-4 is expressed in most epithelial cells yet is absent in mesothelial cells, making it of great use in characterizing epithelial malignincies.³ Immunohistochemical identification of this antigen may help identify poorly differentiated lung adenocarcinoma from lesions of mesothelial origin.⁴ Likewise, identification of claudin-4 expression by IHC may be useful in characterizing breast and endometrial lesions.^5,6

Qualità

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2