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30549

Sigma-Aldrich

Kollicoat® IR

Sinonimo/i:

Macrogol-poly(vinyl alcohol) graft-copolymer, Polyvinyl alcohol-polyethylene glycol graft-copolymer

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About This Item

Numero CAS:
96734-39-3
Codice UNSPSC:
12162002
NACRES:
NA.25

Impurezze

ethylene glycol, complies (meets the requirements of Macrogol Polyvinylalcohol Grafted Copolymer Ph Eur Ed. 7)
≤1 ppm ethylene oxide
≤10 ppm dioxan
≤100 ppm vinyl acetate
≤15000 ppm acetic acid
≤20 ppm heavy metals

Livello qualitativo

200

Residuo alla calcinazione

≤2%

Perdita

≤5% loss on drying

pH

5.0-8.0 (20% in H2O)

Viscosità

50-250 mPa.s, 20 %(23 °C, Brookfield RVT) (SP.2, 100RPM)

Numero di estere

10‑70 mg KOH/g

Applicazioni

Kollicoat IR is used in the pharmaceutical industry as a binder, pellets, and particulate matter. This research grade product is intended for use in R&D and development only.

Note legali

Kollicoat is a registered trademark of BASF SE

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
BCCK3276
BCCG4258
BCCF7577
BCCD9009
BCCB8029

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Sandra Guns et al.
Pharmaceutical research, 28(3), 673-682 (2010-11-26)
To investigate the effect of the manufacturing method (spray-drying or hot-melt extrusion) on the kinetic miscibility of miconazole and the graft copolymer poly(ethyleneglycol-g-vinylalcohol). The effect of heat pre-treatment of solutions used for spray-drying and the use of spray-dried copolymer as
Susanne Muschert et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(1), 130-137 (2009-01-17)
The aim of this study was to better understand the underlying drug release mechanisms from aqueous ethylcellulose-coated pellets containing different types of drugs and starter cores. Theophylline, paracetamol, metoprolol succinate, diltiazem HCl and metoprolol tartrate were used as model drugs
Kyung Jin Son et al.
ACS applied materials & interfaces, 3(2), 573-581 (2011-02-05)
In this study, we describe the use of organized mesoporous titanium oxide (TiO(2)) films as three-dimensional templates for protein microarrays with enhanced protein loading capacity and detection sensitivity. Multilayered mesoporous TiO(2) films with high porosity and good connectivity were synthesized
Pan Liu et al.
Journal of pharmaceutical sciences, 101(8), 2811-2820 (2012-05-23)
The objective of this study was to investigate the drug release mechanism and in vivo performance of Tanshinone IIA sustained-release pellets, coated with blends of polyvinyl acetate (PVAc) and poly(vinyl alcohol)-poly(ethylene glycol) (PVA-PEG) graft copolymer. A formulation screening study showed

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