259A-1

Glucagon Rabbit Polyclonal Antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: Ig fraction of antiserum
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (259A-14); vial of 0.5 mL concentrate (259A-15); bottle of 1.0 mL predilute (259A-17); vial of 1.0 mL concentrate (259A-16); bottle of 7.0 mL predilute (259A-18)
• Produttore/marchio commerciale: Cell Marque^™
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• Controllo: pancreas
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: cytoplasmic
• Informazioni sul gene: human ... GCG(2641)

Descrizione

Descrizione generale

The normal islets of Langerhans (pancreas) contain four major cell types, 15-20% of which are alpha cells which produce glucagon. Alpha cell tumors can be divided into two distinct types; those associated with glucagonoma syndrome (necrolytic migratory erythema, diabetes, anemia, stomatitis, weight loss, venous thromboses, diarrhea, and sometimes psychiatric disturbances), and those which are not. Those associated with the syndrome tend to be large and solitary and there is a high incidence of malignancy. Those glucagonomas not associated with the syndrome tend to be multiple and small and are nearly always benign.Immunohistochemically, the two types of glucagonoma are reactive to the glucagon antibody, though occasionally only weakly.

Qualità

IVD

IVD

IVD

RUO

Linkage

Glucagon (polyclonal) Positive Control Slides, Product No. 259S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany