113R-2

CD13 (EP117) Rabbit Monoclonal Primary Antibody

• Sinonimo/i: Aminopeptidase-N
• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: EP117, monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (113R-24); vial of 0.1 mL concentrate Research Use Only (113R-24-RUO); vial of 0.5 mL concentrate (113R-25); vial of 1.0 mL concentrate (113R-26); vial of 1.0 mL concentrate Research Use Only (113R-26-RUO); vial of 1.0 mL pre-dilute Research Use Only (113R-27-RUO); vial of 1.0 mL pre-dilute ready-to-use (113R-27); vial of 7.0 mL pre-dilute ready-to-use (113R-28); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (113R-28-RUO)
• Produttore/marchio commerciale: Cell Marque^™
• Concentrazione: 0.1-5 μg/mL (predilute); 2.5-125 μg/mL (concentrate)
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotipo: IgG
• Controllo: liver
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: cytoplasmic, membranous
• Informazioni sul gene: human ... ANPEP(290)

Descrizione

Descrizione generale

CD13 (aminopeptidase-N) is a transmembrane protease present in many tissues and cell types (e.g., endothelial and epithelial cells, fibroblasts, and leukocytes). CD13 is expressed in various solid and hematological malignancies in humans and is useful in identifying acute myeloid leukemia when used in a panel including antibodies against CD13(+), CD34(+), CD117(+), CD16(-), and CD33(+). This protein is also expressed in myeloid sarcoma and anti-CD13 is useful in its identification using a panel.

In addition, it has been reported that CD13 is expressed in both normal and neoplastic liver tissue, where it exhibits a canalicular distribution pattern similar to that seen for polyclonal CEA and CD10. Thus, anti-CD13 can be useful as an additional marker in differentiating between HCC and non-hepatocellular neoplasms.

Qualità

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Linkage

CD13 Positive Control Slides, Product No. 113S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable