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Key Documents

Altri documenti

S2002

Sigma-Aldrich

Sodium azide

ReagentPlus®, ≥99.5%

Sinonimo/i:

Hydrazoic acid sodium salt

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About This Item

Formula condensata:
NaN3
Numero CAS:
26628-22-8
Peso molecolare:
65.01
Numero CE:
247-852-1
Numero MDL:
MFCD00003536
Codice UNSPSC:
12352201
ID PubChem:
24899504
NACRES:
NA.21

Origine biologica

synthetic (inorganic)

Livello qualitativo

200

Nome Commerciale

ReagentPlus®

Saggio

≥99.5%

Forma fisica

powder

Condizioni di stoccaggio

(Tightly closed. Dry. Keep in a well-ventilated place. Do not store near acids.)

tecniche

cell based assay: suitable
immunohistochemistry: suitable

Colore

white

Punto di fusione

370-425 °C

Solubilità

soluble 65 g/L at 20 °C (completely)

Compatibilità

suitable for chromatography
suitable for derivatization

applicazioni

sample preparation

Stringa SMILE

[Na]N=[N+]=[N-]

InChI

1S/N3.Na/c1-3-2;/q-1;+1
PXIPVTKHYLBLMZ-UHFFFAOYSA-N

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Descrizione generale

Sodium Azide (NaN3) is a potent inhibitor – a water-soluble crystalline powder that′s odorless. Widely recognized for its versatile applications, it plays a pivotal role across molecular biology, cell culture, and biochemical research. Sodium azide is commonly used as a bacteriostatic preservative in aqueous laboratory reagents and biological fluids. It is also a metabolic inhibitor, which inhibits oxidative phosphorylation. In cell culture, it maintains the integrity of your cell lines by preventing microbial contamination. Its application extends to molecular biology, where it aids in preserving nucleic acids for downstream analysis, ensuring the fidelity of your results.

Applicazioni

Baylis-Hillman acetates such as ethyl 2-(acetoxyphenylmethyl)acrylate can undergo nucleophilic displacement by sodium azide in aqueous medium to form ethyl (E)-2-azidomethyl-3-phenylpropenoate.
Sodium azide is suitable for use in histopathology to prepare and store tissue samples. Also used as a component of staining buffer (HEPES buffer) for whole mount immunolabelling.
Catalyst for:

  • Oxidative decarboxylation
  • Michael addition reactions

Reagent for synthesis of
  • Blue fluorescent copolymers
  • Metal phosphonates
  • Arenes via aminations

Azioni biochim/fisiol

Sodium azide is clinically used as a preservative in diluting fluid for counting red blood cells. It prevents capping and internalization of fluorescent surface-bound antibodies in various scientific applications, including flow cytometry.

Altre note

For additional information on our range of Biochemicals, please complete this form.

Note legali

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Guanti suggeriti per la protezione dagli schizzi

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Avvertenze

Danger

Indicazioni di pericolo

H300 + H310 + H330,H373,H410

Classi di pericolo

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral

Organi bersaglio

Brain

Rischi supp

EUH032

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
STBK6449
STBK6450
STBK5137
STBK5136
MKCQ1781

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Supelco

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Sodium azide extra pure, Technipur®

Sigma-Aldrich

1.06688

Sodium azide

Nucleophilic displacement by azide and cyanide on Baylis-Hillman acetates in water.
Yadav JS, et al.
Tetrahedron Letters, 46(16), 2761-2763 (2005)
Calcium uptake by rat kidney mitochondria.
DeLuca HF and Engstrom GW.
Proceedings of the National Academy of Sciences of the USA, 47(11), 1744-1750 (1961)
Sodium azide, a bacteriostatic preservative contained in commercially available laboratory reagents, influences the responses of human platelets via the cGMP/PKG/VASP pathway.
Russo I, et al.
Clinical Biochemistry, 41(4), 343-349 (2008)
Xiaohua Sun et al.
Organic letters, 9(22), 4495-4498 (2007-10-04)
A novel intermolecular cross-double-Michael addition between nitro and carbonyl activated olefins has been developed through Lewis base catalysis. The reaction took place with a large group of beta-alkyl nitroalkenes and alpha,beta-unsaturated ketone/esters, producing an allylic nitro compound in good to
Y. Wada, et al.,
Tetrahedron, 65, 1059-1062 (2009)
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