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Key Documents

PHR1520

Supelco

Chlortetracycline Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

Chlortetracycline hydrochloride, 7-Chlorotetracycline hydrochloride

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About This Item

Formula empirica (notazione di Hill):
C22H23ClN2O8 · HCl
Numero CAS:
Peso molecolare:
515.34
Beilstein:
3858364
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to BP 783
traceable to Ph. Eur. C2000000
traceable to USP 1129007

Famiglia di API

chlortetracycline

CdA

current certificate can be downloaded

Confezionamento

pkg of 500 mg

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

210-215 °C (dec.) (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

-10 to -25°C

Stringa SMILE

Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O

InChI

1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1
CBHYYLPALVVVEY-LYNLVHCPSA-N

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Descrizione generale

Chlortetracycline Hydrochloride is a salt of chlortetracycline, which is a tetracycline which shows broad-spectrum antibiotic activity. It is generally used as a veterinary and aquaculture medicine. It is often used on dairy cattle and aquacultured catfish, salmon, and lobster.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Applicazioni

Chlortetracycline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAC3430 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pittogrammi

Health hazardExclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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Determination of tetracycline residues in shrimp and whole milk using liquid chromatography with ultraviolet detection and residue confirmation by mass spectrometry
Andersen WC, et al.
Analytica Chimica Acta, 529(1-2), 145-150 (2005)
The spectrophotometric assay for chlortetracycline HCl and tetracycline HCl in pharmaceuticals
Chiccarelli FS, et al.
Journal of the American Pharmaceutical Association, 48(5), 263-268 (1959)

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