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Documenti fondamentali

PHR1299

Supelco

Pamabrom

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

Pamabrom, PAM

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About This Item

Numero CAS:
Numero CE:
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to USP 1077708

Famiglia di API

pamabrom

CdA

current certificate can be downloaded

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-30°C

InChI

1S/C7H7BrN4O2.C4H11NO/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14;1-4(2,5)3-6/h1-2H3,(H,9,10);6H,3,5H2,1-2H3
ATOTUUBRFJHZQG-UHFFFAOYSA-N

Descrizione generale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pamabrom is a weak diuretic which is used as an analgesic and an antihistamine for symptomatic control of the premenstrual syndrome. It typically assists in the reduction of bloating associated with premenstrual syndrome.

Applicazioni

Pamabrom may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAA0585 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Guillermo Di Girolamo et al.
Expert opinion on pharmacotherapy, 5(3), 561-570 (2004-03-12)
Primary dysmenorrhoea is the most frequent gynaecological condition, with a prevalence of 40 - 90% in women within the reproductive age. It is characterised by cyclic pelvic pain related to menstrual period, vomiting and headache. As prostaglandins and leukotrienes appear
Jil K Swanson et al.
Journal of drugs in dermatology : JDD, 5(3), 284-286 (2006-04-01)
Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms. An urticarial eruption, with systemic complaints consistent with a serum sickness-like reaction, attributed to Pamabron is described. A review of the literature concerning Pamabron and dermatology is discussed.
S Nedorost et al.
Cleveland Clinic journal of medicine, 58(1), 33-34 (1991-01-01)
A young woman presented with recurrent skin lesions that were predominantly perioral. Fixed drug reaction was diagnosed based on her history of intermittent ingestion of Pamprin, a common menstrual symptom reliever, and characteristic erythematous, pigmented, edematous patches. After oral challenge
Development and Validation of Three Spectrophotometric Methods for Simultaneous Determination of Paracetamol and Pamabrom in Bulk and Pharmaceutical Formulation
Abdelaleem EA, et al.
Analytical Chemistry Letters, 6(1), 13-23 (2016)
Fixed drug eruptions and oral rechallenge.
K Kauppinen
Cleveland Clinic journal of medicine, 58(1), 64-65 (1991-01-01)

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