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Documenti fondamentali

PHR1117

Supelco

2,6-di-tert-butil-4-metilfenolo

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

2,6-di-tert-butil-p-cresolo, BHT, Butilidrossitoluene, DBPC, Idrossitoluene butilato

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About This Item

Formula condensata:
[(CH3)3C]2C6H2(CH3)OH
Numero CAS:
Peso molecolare:
220.35
Beilstein:
1911640
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
Numero E:
E321
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to Ph. Eur. B1215000
traceable to USP 1092708

Densità del vapore

7.6 (vs air)

Tensione di vapore

<0.01 mmHg ( 20 °C)

Famiglia di API

butylated hydroxytoluene

CdA

current certificate can be downloaded

Temp. autoaccensione

878 °F

tecniche

HPLC: suitable
gas chromatography (GC): suitable

P. eboll.

265 °C (lit.)

Punto di fusione

69-73 °C (lit.)

applicazioni

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3
NLZUEZXRPGMBCV-UHFFFAOYSA-N

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Descrizione generale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Butylated hydroxytoluene (BHT) is a phenolic antioxidant used as a food additive. It is frequently added to dried cereals, cooking oils and animal foods. BHT is also known to enhance the stability of pharmaceuticals, fat-soluble vitamins and cosmetics .

Applicazioni

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAB3695 in the slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Environment

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Aquatic Acute 1 - Aquatic Chronic 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

260.6 °F - open cup

Punto d’infiammabilità (°C)

127 °C - open cup


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Certificati d'analisi (COA)

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I clienti hanno visto anche

Reactivity of butylated hydroxytoluene.
Lambert CR, et al.
Free Radical Biology & Medicine, 21(3), 395-400 (1996)
Deliang Guo et al.
Science signaling, 2(101), ra82-ra82 (2009-12-17)
Glioblastoma, the most common malignant brain tumor, is among the most lethal and difficult cancers to treat. Although epidermal growth factor receptor (EGFR) mutations are frequent in glioblastoma, their clinical relevance is poorly understood. Studies of tumors from patients treated
Hiroya Okamoto et al.
Experimental dermatology, 21 Suppl 1, 5-7 (2012-06-01)
Pt nanoparticle is a strong reductant and has been used as an antioxidant in cosmetics and medicine. It was reported to have catalase-like activity, which converts hydrogen peroxide to water and oxygen. However, in this study, freshly prepared Pt nanoparticle
A M Malkinson
Environmental mutagenesis, 5(3), 353-362 (1983-01-01)
Although the average American's daily consumption of BHT can be measured in milligrams, there are numerous reports that BHT causes organ damage in laboratory animals. Only a few genotoxic effects of BHT have been reported, however, including mutagenicity in the
Metabolism and pulmonary toxicity of butylated hydroxytoluene (BHT).
H Witschi et al.
Pharmacology & therapeutics, 42(1), 89-113 (1989-01-01)

Protocolli

HPLC Analysis of Phenolic Antioxidants on Ascentis® Express C18 2.7 μm

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