Passa al contenuto
Merck
Tutte le immagini(1)

Key Documents

D6003

Supelco

Digoxin

analytical standard

Sinonimo/i:

12β-Hydroxydigitoxin

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Formula empirica (notazione di Hill):
C41H64O14
Numero CAS:
Peso molecolare:
780.94
Beilstein:
77011
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Origine biologica

plant (Digitalis lanata)

Livello qualitativo

Grado

analytical standard

Saggio

≥95.0% (HPLC)

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Solubilità

methanol: methylene chloride (1:1): 0.5%, clear, colorless

applicazioni

food and beverages
forensics and toxicology
veterinary

Formato

neat

Gruppo funzionale

ketone

Condizioni di spedizione

ambient

Temperatura di conservazione

room temp

Stringa SMILE

C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]2[C@@H](O)C[C@@H](O[C@@H]2C)O[C@H]3[C@@H](O)C[C@@H](O[C@@H]3C)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4

InChI

1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1
LTMHDMANZUZIPE-PUGKRICDSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Applicazioni

Digoxin may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

A cardiac glycoside, substrate for Pgp, upregulates Pgp expression and down regulates SXR (Steroid Xenobiotic Receptor).

Pittogrammi

Skull and crossbonesHealth hazard

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 4

1 of 4

Lanatoside C ≥97% (TLC)

Sigma-Aldrich

L2261

Lanatoside C

Digitoxin European Pharmacopoeia (EP) Reference Standard

D1800000

Digitoxin

Lanatoside C phyproof® Reference Substance

PHL82573

Lanatoside C

Simultaneous determination of digoxin and permeability markers in rat in situ intestinal perfusion samples by RP-HPLC
Varma.S.V M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 813(1-2), 347-352 (2004)
Combined liquid chromatography/radioimmunoassay with improved specificity for serum digoxin
Gault H.M, et al.
Clinical Chemistry, 31(8), 1272-1277 (1985)
Melanie L Lawrence et al.
Scientific reports, 5, 9092-9092 (2015-03-15)
Recent advances in renal tissue engineering have shown that dissociated, early renogenic tissue from the developing embryo can self-assemble into morphologically accurate kidney-like organs arranged around a central collecting duct tree. In order for such self-assembled kidneys to be useful
Andrew Nickless et al.
Nature medicine, 20(8), 961-966 (2014-07-30)
The nonsense-mediated mRNA decay (NMD) pathway selectively eliminates aberrant transcripts containing premature translation termination codons and regulates the levels of a number of physiological mRNAs. NMD modulates the clinical outcome of a variety of human diseases, including cancer and many
Adriana Katz et al.
The Journal of biological chemistry, 289(30), 21153-21162 (2014-06-12)
In the ciliary epithelium of the eye, the pigmented cells express the α1β1 isoform of Na,K-ATPase, whereas the non-pigmented cells express mainly the α2β3 isoform of Na,K-ATPase. In principle, a Na,K-ATPase inhibitor with selectivity for α2 could effectively reduce intraocular

Protocolli

LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.