Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

Visualizza tutta la documentazione

C0166000

Calcifediol

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

25-Hydroxyvitamin D3 monohydrate, 25-Hydroxycholecalciferol

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula empirica (notazione di Hill):
C27H44O2 · H2O
Numero CAS:
63283-36-3
Peso molecolare:
418.65
Beilstein:
4270041
Numero MDL:
MFCD00867077
Codice UNSPSC:
41116107
ID PubChem:
329774765
NACRES:
NA.24

Origine biologica

sheep wool (grease)

Grado

pharmaceutical primary standard

agenzia

EP

Famiglia di API

calcifediol

Forma fisica

solid

Produttore/marchio commerciale

EDQM

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
JWUBBDSIWDLEOM-DTOXIADCSA-N

Informazioni sul gene

human ... VDR(7421)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Categorie correlate

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.Calcifediol is a biologically active metabolite of vitamin D. It is more hydrophilic and better absorbed in the intestine when compared to ergocalciferol or cholecalciferol due to the high affinity for the vitamin-D-binding protein. The drug is known to treat diseases associated with decreased intestinal absorption and obesity.

Applicazioni

Calcifediol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H301 + H311,H330,H372

Classi di pericolo

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

Ci dispiace, ma al momento non ci sono COA disponibili online per questo prodotto.

Se ti serve aiuto, non esitare a contattarci Servizio Clienti

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 7

1 of 7

25-Hydroxyvitamin D calibration solutions NIST® SRM® 2972a

NIST2972A

25-Hydroxyvitamin D calibration solutions

25-Hydroxyvitamin D3 solution 100 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

H-083

25-Hydroxyvitamin D3 solution

USP

USP

1086301

Calcitriol

Colecalciferolo (D3) analytical standard

Supelco

47763

Colecalciferolo (D3)

1α,25-diidrossivitamina D3 ≥99% (HPLC)

Sigma-Aldrich

D1530

1α,25-diidrossivitamina D3

Colecalciferolo ≥98% (HPLC)

Sigma-Aldrich

C9756

Colecalciferolo

Ergocalciferol ≥98.0% (sum of enantiomers, HPLC)

Sigma-Aldrich

95220

Ergocalciferol

Hypovitaminosis D: is it time to consider the use of calcifediol?
Cesareo R, et al.
Nutrients, 11(5), 1016-1016 (2019)
Kristyna Brabnikova-Maresova et al.
Arthritis research & therapy, 16(5), 460-460 (2014-10-05)
Juvenile idiopathic arthritis (JIA) is a disease associated with loss of bone mass, deterioration in bone mass quality and an increased risk of fractures. The objective of this study was to evaluate factors that predict bone mineral density (BMD) alterations
Stuart M Sprague et al.
American journal of nephrology, 40(6), 535-545 (2015-01-13)
Vitamin D insufficiency drives secondary hyperparathyroidism (SHPT) and is associated with increased cardiovascular mortality in patients with chronic kidney disease (CKD). SHPT is poorly addressed by current vitamin D repletion options. The present study evaluated a novel investigational vitamin D
Ting-I Lee et al.
International journal of cardiology, 176(1), 151-157 (2014-07-27)
High free fatty acid with reduced glucose utilization in diabetes mellitus (DM) impairs cardiac function. Peroxisome proliferator-activated receptors (PPARs) modulate myocardial lipid and glucose homeostasis. The active 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) regulates oxidative stress and inflammation, which may play a key
Cécile Meunier et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 989, 54-61 (2015-03-25)
Many methods for routine total plasma/serum 25-hydroxyvitamin D (25OHD) measurements are available from automated immunoassays to the most specific LC-MS/MS techniques. These last ones are nowadays numerous, still perfectible but more powerful than immunoassays in specific illnesses. We presented a
Visualizza tutti i documenti correlati

Articoli

LC/MS/MS Analysis of Vitamin D Metabolites on Ascentis® Express F5

This application shows an Ascentis Express F5 provided rapid resolution of the isobaric vitamin D metabolites. MS detection provides the necessary secondary resolution.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.