90970

γ-Butyrolactone

analytical standard

• Sinonimo/i: γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL
• Formula empirica (notazione di Hill): C₄H₆O₂
• Numero CAS: 96-48-0
• Peso molecolare: 86.09
• Beilstein: 105248
• Numero CE: 202-509-5
• Numero MDL: MFCD00005386
• Codice UNSPSC: 85151701
• ID PubChem: 329769980
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Densità del vapore: 3 (vs air)
• Tensione di vapore: 1.5 mmHg ( 20 °C)
• Saggio: ≥99.0% (GC)
• Temp. autoaccensione: 851 °F
• Durata: limited shelf life, expiry date on the label
• Limite di esplosione: 16 %
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Impurezze: ≤0.3% water
• Indice di rifrazione: n20/D 1.436 (lit.)
• P. ebollizione: 204-205 °C (lit.)
• Punto di fusione: −45 °C (lit.)
• Densità: 1.12 g/mL at 25 °C (lit.)
• applicazioni: cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O=C1CCCO1
• InChI: 1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2; YEJRWHAVMIAJKC-UHFFFAOYSA-N

Descrizione

Descrizione generale

γ-Butyrolactone (GBL) is a related lactone analog of γ-hydroxybutyric acid (GHB), a widespread drug of abuse, identified as an endogenous constituent of the mammalian brain, in which it exhibits a strong central nervous system depressant effect. GBL is considered as a legal substitute of GHB, and commonly identified in beverages including coffee, apple cider vinegar, tea, carbonated drinks, etc.

Applicazioni

γ-Butyrolactone may be used as an analytical reference standard for the quantification of the analyte in roasted Italian chestnuts, wine samples, beverages using chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.

Informazioni sulla sicurezza

• Pittogrammi: GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H318,H336
• Consigli di prudenza: P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• Organi bersaglio: Central nervous system
• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 208.4 °F - closed cup
• Punto d’infiammabilità (°C): 98 °C - closed cup