Passa al contenuto
Merck
Tutte le immagini(2)

Key Documents

View All Documentation

49702

Supelco

Carnosol

analytical standard

Sinonimo/i:

Picrosalvin

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(2)

About This Item

Formula empirica (notazione di Hill):
C20H26O4
Numero CAS:
5957-80-2
Peso molecolare:
330.42
Numero MDL:
MFCD02752467
Codice UNSPSC:
85151701
ID PubChem:
329757507
NACRES:
NA.24

Origine biologica

Rosemarinus officinalis L. leaves

Livello qualitativo

100

Grado

analytical standard

Saggio

≥98.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

CC(C)c1cc2[C@@H]3C[C@H]4C(C)(C)CCC[C@]4(C(=O)O3)c2c(O)c1O

InChI

1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1
XUSYGBPHQBWGAD-PJSUUKDQSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Carnosol is a naturally occurring phyto polyphenolor phenolic diterpene, found in rosemary, which can show a broad spectrum of applications as a an antioxidant, anticancer agent and anti-inflammatory agent.
Carnosol is one of the phenolic antioxidants present in extracts of the herb rosemary (Rosmarinus officinalis). Carnosol inhibits the formation of tumors derived using irritants such as TPA and DMBA in murine models of carcinogenesis.The effective dose reported is 1-10 μM topically or 6 μg/ml when added to supernatants of cultured cells.Addition of rosemary extracts to the diet as a 1% supplement by weight was also found to decrease the frequency of DMBA-DNA adducts.

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

A phenolic diterpene with antioxidant and anticarcinogenic activities.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

This compound is commonly found in plants of the genus: salvia

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H317

Consigli di prudenza

P280 - P302 + P352

Classi di pericolo

Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
BCCG9960
BCCF9705
BCCF3139
BCCF1273
BCCD9815

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 8

1 of 8

Rosmarinic acid ≥98% (HPLC), from Rosemarinus officinalis L.

Sigma-Aldrich

R4033

Rosmarinic acid

USP

USP

1605680

Powdered Rosemary Hydrophilic Extract

Rosmarinic acid 96%

Sigma-Aldrich

536954

Rosmarinic acid

USP

USP

1605668

Powdered Rosemary Extract

(+)-Borneol analytical standard

Supelco

68878

(+)-Borneol

(1S)-(−)-Verbenone analytical standard

Supelco

94882

(1S)-(−)-Verbenone

(−)-Bornyl acetate analytical standard

Supelco

45855

(−)-Bornyl acetate

Rosmarinic acid primary reference standard

00390580

Rosmarinic acid

Ai-Hsiang Lo et al.
Carcinogenesis, 23(6), 983-991 (2002-06-26)
Carnosol is a naturally occurring phytopolyphenol found in rosemary. Carnosol functions as antioxidant and anticarcinogen. In the present study, we compared the antioxidant activity of carnosol and other compounds extracted from rosemary. Carnosol showed potent antioxidative activity in alpha,alpha-diphenyl-beta-picrylhydrazyl (DPPH)
Carnosol: a promising anti-cancer and anti-inflammatory agent
Johnson.JJ
Cancer Letters, 305, 1-7 (2011)
Shiu-Chen Huang et al.
Biochemical pharmacology, 69(2), 221-232 (2005-01-04)
Carnosol, a constant constituent of Rosmarinus officinalis extracts, is a phenolic diterpene shown to have antioxidant and anticarcinogen properties. In our studies, carnosol inhibited the invasion of highly metastatic mouse melanoma B16/F10 cells in vitro. First, the antimetastatic potentials of
Kai-Cheng Lian et al.
Toxicology and applied pharmacology, 245(1), 21-35 (2010-02-02)
The increased adhesion of monocytes to injured endothelial layers is a critical early event in atherogenesis. Under inflammatory conditions, there is increased expression of specific cell adhesion molecules on activated vascular endothelial cells, which increases monocyte adhesion. In our current
Sang Yong Kim et al.
Journal of agricultural and food chemistry, 58(3), 1543-1550 (2010-01-16)
Carnosol, a naturally occurring bioactive phenolic diterpene originating from rosemary and sage, has been shown to exert antioxidant and anti-inflammatory effects. This study examined possible protective effects of carnosol on sodium nitroprusside (SNP)-induced cytotoxicity in C6 glial cells. Carnosol (1-10
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.