437573

N,N-dimetilformammide

ACS reagent, ≥99.8%

• Sinonimo/i: DMF, NSC 5356
• Formula condensata: HCON(CH₃)₂
• Numero CAS: 68-12-2
• Peso molecolare: 73.09
• Beilstein: 605365
• Numero CE: 200-679-5
• Numero MDL: MFCD00003284
• Codice UNSPSC: 12352111
• ID PubChem: 24867382

Proprietà

• Grado: ACS reagent
• Livello qualitativo: 200
• Densità del vapore: 2.5 (vs air)
• Tensione di vapore: 2.7 mmHg ( 20 °C)
• Saggio: ≥99.8%
• Forma fisica: liquid
• Temp. autoaccensione: 833 °F
• Limite di esplosione: 15.2 %
• tecniche: electrophoresis: suitable
• Impurezze: ≤0.0005 meq/g Titr. acid; ≤0.003 meq/g Titr. base; ≤0.15% water
• Residuo dopo evaporazione: ≤0.005%
• Colore: APHA: ≤15
• Indice di rifrazione: n20/D 1.430 (lit.)
• pH: 6.7
• P. eboll.: 153 °C (lit.)
• Punto di fusione: −61 °C (lit.)
• Solubilità: water: miscible
• Densità: 0.944 g/mL (lit.)
• Stringa SMILE: [H]C(=O)N(C)C
• InChI: 1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3; ZMXDDKWLCZADIW-UHFFFAOYSA-N

Descrizione

Descrizione generale

N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.

Applicazioni

N,N-Dimethylformamide (DMF) may be used in the following processes:

• As a solvent synthesis of gold nanoparticles.
• As a solvent in capillary electrophoresis.
• Regioselective synthesis of N,N-dimethylaminopyridzines by reacting with choropyridazines.
• Synthesis of urea-N,N-dimethylformamide, a 3:1 solvate with urea.

Solvente per molti composti organici idrofobi.

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H226,H312 + H332,H319,H360D
• Consigli di prudenza: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): 135.5 °F - closed cup
• Punto d’infiammabilità (°C): 57.5 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter