383376

Potassium antimonyl tartrate trihydrate

ACS reagent, ≥99%

• Sinonimo/i: Antimony potassium tartrate trihydrate, Tartar emetic
• Formula empirica (notazione di Hill): C₈H₄K₂O₁₂Sb₂ · 3H₂O
• Numero CAS: 28300-74-5
• Peso molecolare: 667.87
• Numero CE: 234-293-3
• Numero MDL: MFCD00167056
• Codice UNSPSC: 12352100
• ID PubChem: 24863959
• NACRES: NA.21

Proprietà

• Grado: ACS reagent
• Livello qualitativo: 200
• Saggio: ≥99%; 99.0-103.0%
• Forma fisica: powder
• Impurezze: ≤0.020 meq/g Titr. acid or base
• Perdita: ≤2.7% loss on drying
• Punto di fusione: ≥300 °C (lit.)
• Solubilità: water: soluble
• Cationi in tracce: As: ≤0.015%
• Stringa SMILE: O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
• InChI: 1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4; WBTCZEPSIIFINA-UHFFFAOYSA-J

Descrizione

Descrizione generale

Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII). Potassium antimonyl tartrate (PAT) is an antiparasitic agent predominantly used for treating infections caused by the parasite Leishmania. Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells. Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.

Applicazioni

Potassium antimonyl tartrate trihydrate has been used in the dose-inhibition experiments to evaluate the dose-inhibition curves of antimony-based antileishmanial compounds against Leishmania promastigotes in medium 199.

Potassium antimonyl tartrate trihydrate may be used to prepare antimony (Sb(III)) stock solution in deionized water (100mg/L). It may also be employed in the spectrophotometric determination of total phosphorus in dry sediments.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H301,H315,H317,H332,H411
• Consigli di prudenza: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312
• Classi di pericolo: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves