32460

Meropenem trihydrate

VETRANAL^®, analytical standard

• Sinonimo/i: (1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate
• Formula empirica (notazione di Hill): C₁₇H₂₅N₃O₅S · 3H₂O
• Numero CAS: 119478-56-7
• Peso molecolare: 437.51
• Numero MDL: MFCD08600005
• Codice UNSPSC: 41116107
• ID PubChem: 329754224
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Nome Commerciale: VETRANAL^®
• Durata: limited shelf life, expiry date on the label
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• applicazioni: forensics and toxicology; pharmaceutical (small molecule)
• Formato: neat
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: O.O.O.C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N2C1=O)C(O)=O
• InChI: 1S/C17H25N3O5S.3H2O/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;;;/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);3*1H2/t7-,8-,9+,10+,11-,12-;;;/m1.../s1; CTUAQTBUVLKNDJ-OBZXMJSBSA-N

Descrizione

Descrizione generale

Meropenem trihydrate (Meropenem) is a broad-spectrum carbapenem with antibacterial properties. It inhibits cell wall synthesis in both gram-negative and gram-positive bacteria.

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Meropenem has been used as a reference standard in an experiment conducted to investigate the effects on in vivo efficacy caused due to chemical differences in three generic products of meropenem.

Meropenem penetrates cell walls and binds to penicillin-binding protein targets. It acts against aerobes and anaerobes including E. coli, Klebsiella, Clostridium, Enterococcus sp. It is a common cause of mild transient aminotransferase elevations and can rarely result in clinically apparent, cholestatic liver injury.

Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic active against both Gram-positive and Gram-negative bacteria.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H317,H334
• Consigli di prudenza: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Classi di pericolo: Resp. Sens. 1 - Skin Sens. 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable