Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

SMB00607

Sigma-Aldrich

Amoxicillin trihydrate: potassium clavulanate (4:1)

Sinonimo/i:

Amoxicillin Trihydrate: Potassium Clavulanate

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Codice UNSPSC:
51285005
NACRES:
NA.85

Stato

powder

Livello qualitativo

200

Condizioni di stoccaggio

(Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.)

Colore

white to yellow

Spettro attività antibiotica

Gram-negative bacteria
Gram-positive bacteria

Modalità d’azione

cell wall synthesis | interferes

Temperatura di conservazione

2-8°C

Descrizione generale

Amoxicillin trihydrate is a semisynthetic antibiotic, that is used as a medicine.

Applicazioni

Amoxicillin trihydrate: potassium clavulanate (4:1) has been used to study its effect on the viral déjà vu disease (neonatal intracerebral (i.c.) infection) in mice model.

Azioni biochim/fisiol

Amoxicillin trihydrate is a broad-spectrum, β-lactam antibiotic. It inhibits the cross-linkage between linear peptidoglycan polymer chains that are the major component of both Gram-positive and Gram-negative bacteria. Since amoxicillin is degraded by β-lactamases, it does not show activity against bacteria which produce these enzymes.

Clavulanate is a β-lactam antibiotic related to the penicillins. Clavulanate competitively and irreversibly inhibits a wide variety of β-lactamases found in bacteria that are resistant to penicillins and cephalosporins.

Formulations of amoxicillin with clavulanic acid prevent the degradation of amoxicillin by β-lactamase enzymes. This increases amoxicillin′s antibacterial activity against bacteria normally resistant to β-lactam antibiotics.

Confezionamento

1G

Componenti

Material is a powdered mixture of 4 parts amoxicillin trihydrate to 1 part potassium clavulanate.

Stoccaggio e stabilità

Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.

Altre note

Keep container tightly closed in a dry and well-ventilated place. Never allow product to get in contact with water during storage.

Pittogrammi

FlameHealth hazard
GHS02,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H228,H252,H317,H334

Classi di pericolo

Flam. Sol. 2 - Resp. Sens. 1 - Self-heat. 2 - Skin Sens. 1

Rischi supp

EUH014,EUH044

Codice della classe di stoccaggio

4.2 - Pyrophoric and self-heating hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
128M4800V
077M4891V
096M4875V

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 6

1 of 6

Amoxicillin trihydrate British Pharmacopoeia (BP) Reference Standard

BP019

Amoxicillin trihydrate

vibrant-m

Y0001168

Potassium clavulanate impurity G

Cefuroxime sodium salt

Supelco

C4417

Cefuroxime sodium salt

Cefazolin sodium salt 89.1-110.1%

Sigma-Aldrich

C5020

Cefazolin sodium salt

Cotrimoxazole, Ready Made Solution 100 mg/mL in DMSO

Sigma-Aldrich

A2487

Cotrimoxazole, Ready Made Solution

Amikacin sulfate salt aminoglycoside antibiotic

Sigma-Aldrich

A2324

Amikacin sulfate salt

Preparation and characterization of Sn/Zn/TiO2 photocatalyst for enhanced amoxicillin trihydrate degradation
Mohammadi R, et al.
Desalination and Water Treatment, 53(7), 1995-2004 (2015)
R N Brogden et al.
Drugs, 18(3), 169-184 (1979-09-01)
Amoxycillin, an acid stable semisynthetic penicillin shown to be effective against a wide range of infections when given orally, is now available for intramuscular and intravenous injection. Amoxycillin has an antibacterial spectrum and level of activity essentially the same as
In vitro antimicrobial activity of 6(D(-) -amino-p-hydroxyphenylacetamido) penicillanic acid, a new semisynthetic penicillin.
H C Neu et al.
Antimicrobial agents and chemotherapy, 10, 407-410 (1970-01-01)
Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
Di Liberto G, et al.
Cell (2018)
A P Ball et al.
Lancet (London, England), 1(8169), 620-623 (1980-03-22)
Clavulanic acid is an inhibitor of certain beta-lactamases, notably those enzymes which inactivate the penicillins and cause resistance of important bacteria to these antibiotics. Microbiological, pharmacological, and clinical studies show that clavulanic acid in combination with amoxycillin is effective and
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.