247588

Salicylic acid

ACS reagent, ≥99.0%

• Sinonimo/i: 2-Hydroxybenzoic acid
• Formula condensata: 2^-(HO)C₆H₄CO₂H
• Numero CAS: 69-72-7
• Peso molecolare: 138.12
• Beilstein: 774890
• Numero CE: 200-712-3
• Numero MDL: MFCD00002439
• Codice UNSPSC: 12352100
• ID PubChem: 24854876
• NACRES: NA.21

Proprietà

• Grado: ACS reagent
• Livello qualitativo: 200
• Densità del vapore: 4.8 (vs air)
• Tensione di vapore: 1 mmHg ( 114 °C)
• Saggio: ≥99.0%
• Impurezze: H₂SO₄, passes test (darkened)
• Residuo alla calcinazione: ≤0.01%
• P. eboll.: 211 °C (lit.)
• Punto di fusione: 158-161 °C (lit.)
• Anioni in tracce: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.003%
• Cationi in tracce: Fe: ≤2 ppm; heavy metals (as Pb): ≤5 ppm
• Stringa SMILE: OC(=O)c1ccccc1O
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10); YGSDEFSMJLZEOE-UHFFFAOYSA-N
• Informazioni sul gene: human ... ALB(213) , PTPN1(5770)

Descrizione

Descrizione generale

Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.

Applicazioni

Salicylic acid has been used:

• as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
• as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)

Azioni biochim/fisiol

Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H318,H361d
• Consigli di prudenza: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 314.6 °F - closed cup
• Punto d’infiammabilità (°C): 157 °C - closed cup
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves