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Documenti fondamentali

229253

Sigma-Aldrich

Carminic acid

≥90% (HPLC)

Sinonimo/i:

Natural Red 4

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About This Item

Formula empirica (notazione di Hill):
C22H20O13
Numero CAS:
Peso molecolare:
492.39
Colour Index:
75470
Beilstein:
71651
Numero CE:
Numero MDL:
Codice UNSPSC:
12171500
ID PubChem:
NACRES:
NA.47

Livello qualitativo

Saggio

≥90% (HPLC)

Stato

powder

Attività ottica

[α]20/D +3.1°, c = 1 in H2O

Colore

purple to red-purple
red to very dark red

Punto di fusione

136 °C

Solubilità

1 N acetic acid: 1%, clear to hazy, red

λmax

495 nm

ε (coefficiente d’estinzione)

≥13000 at 222-228  nm in ethanol at 0.03 g/L
≥18000 at 275-281 nm in ethanol at 0.03 g/L

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

Cc1c(C(O)=O)c(O)cc2C(=O)c3c(O)c(O)c([C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(O)c3C(=O)c12

InChI

1S/C22H20O13/c1-4-8-5(2-6(24)9(4)22(33)34)13(25)10-11(15(8)27)16(28)12(18(30)17(10)29)21-20(32)19(31)14(26)7(3-23)35-21/h2,7,14,19-21,23-24,26,28-32H,3H2,1H3,(H,33,34)/t7-,14-,19+,20-,21+/m1/s1
DGQLVPJVXFOQEV-JNVSTXMASA-N

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Descrizione generale

Carmine is a cochineal product usually furnished as an aluminum and calcium salt of carminic acid. Carminic acid is used for human-medical cell diagnosis and serves the purpose of the histological investigation of sample material of human origin. It is suitable for staining nuclei in histological sections. It is utilized in various staining methods including the procedure for detection of glycogen and mucous substances (Best′s carmine), for nuclear staining, or vital staining.

Applicazioni

Carminic acid (CI 75470) is used in Orth′s lithium carmine technique for nuclear staining, Best′s stain for glycogen, and Southgates′s mucicarmine method.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Gabriel J. Lauro, Jack Francis
Natural Food Colorants: Science and Technology (2000)
J.D. Houghton, G.A.F. Hendry
Natural Food Colorants (2012)
Samanan Poowakanjana et al.
Journal of food science, 74(9), C707-C712 (2010-05-25)
Carmine used to color surimi seafood often seeps or bleeds from red-colored meat to white meat when vacuum-packed products go through high-temperature long-time pasteurization. Various physical and chemical treatments were examined to investigate means to inhibit or minimize carmine bleeding
Naoki Sugimoto et al.
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 51(1), 19-27 (2010-03-09)
A quantitative NMR (qNMR) method was applied for the determination of carminic acid. Carminic acid is the main component in cochineal dye that is widely used as a natural food colorant. Since several manufacturers only provide reagent-grade carminic acid, there
Xiao Wang et al.
Biomedical materials (Bristol, England), 6(3), 035010-035010 (2011-05-11)
Tendon disorders are common clinical conditions. Tendon tissue engineering provides a new approach for tendon repair by integrating engineered substitutes with their native counterparts. Silk is considered to be a promising candidate for tendon engineering because of its biological and

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