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Key Documents

15209

Supelco

N,O-Bis(trimetilsilil)trifluoroacetamide con trimetilclorosilano

for GC derivatization, LiChropur, contains 10% TMCS, 98% (excluding TMCS)

Sinonimo/i:

BSTFA + TMCS

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About This Item

Formula condensata:
CF3C[=NSi(CH3)3]OSi(CH3)3
Numero CAS:
Peso molecolare:
257.40
Beilstein:
2050024
Numero MDL:
Codice UNSPSC:
41116105
ID PubChem:
NACRES:
NA.22

Grado

for GC derivatization

Livello qualitativo

Saggio

≥97.5% (excluding TMCS, GC)
98% (excluding TMCS)

Forma fisica

liquid

Qualità

LiChropur

Impiego in reazioni chimiche

reagent type: derivatization reagent
reaction type: Silylations

tecniche

gas chromatography (GC): suitable

Impurezze

9.0-11.0% TMCS

Indice di rifrazione

n20/D 1.384 (lit.)

P. eboll.

45-50 °C/14 mmHg (lit.)

Densità

0.97 g/mL (lit.)

Stringa SMILE

C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F

InChI

1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+
XCOBLONWWXQEBS-KPKJPENVSA-N

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Descrizione generale

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane has found application to be used in gas chromatography (GC) and mass-spectrometry (MS). It can also be used in HPLC- electrochemical detection assay of 8-oxo-deoxyguanosine and?8-oxo-guanine.

Applicazioni


  • Determination of Δ(9)-tetrahydrocannabinol, 11-nor-carboxy-Δ(9)-tetrahydrocannabinol and cannabidiol in human plasma and urine after a commercial cannabidiol oil product intake.: This study uses N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane for derivatization to enhance the sensitivity and accuracy of cannabinoid detection in biological samples. This method is vital for forensic toxicology and clinical research, providing reliable data for cannabinoid analysis (Papoutsis et al., 2024).

  • The impact of lipid degradation on fingerprint quality on fired firearm cartridges.: This research employs N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane to study lipid degradation and its effect on fingerprint quality on firearm cartridges. The findings are crucial for forensic science, particularly in improving methods for preserving and analyzing fingerprint evidence (Goulart et al., 2023).

  • Contaminants of emerging concern: Silylation procedures, evaluation of the stability of silyl derivatives and associated measurement uncertainty.: This paper evaluates the use of N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane in silylation procedures for environmental analysis. The study assesses the stability and measurement uncertainty of silyl derivatives, which is crucial for accurate monitoring of environmental contaminants (Ljoncheva et al., 2023).

  • Screening of Organic Acidurias by Gas Chromatography-Mass Spectrometry (GC-MS).: This research utilizes N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane in the derivatization process for screening organic acidurias. This method is significant for clinical diagnostics, providing a reliable approach for detecting metabolic disorders (Scott et al., 2022).

  • A sensitive, robust method for determining natural and synthetic hormones in surface and wastewaters by continuous solid-phase extraction-gas chromatography-mass spectrometry.: The study presents a method using N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane for the detection of hormones in environmental samples. This robust method is essential for monitoring water quality and detecting endocrine-disrupting compounds (Chafi and Ballesteros, 2022).


Altre note

La posizione dei gruppi silile non è stata definita in maniera inequivocabile. È stata riferita come N,N e N,O.

Note legali

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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N° Catalogo
Descrizione
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Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

15.8 °F - closed cup

Punto d’infiammabilità (°C)

-9 °C - closed cup

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Metabolism of arachidonate through NADPH-dependent oxygenase of renal cortex.
Proceedings of the National Academy of Sciences of the USA, 78 (12), 7375-7378 (1981)
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Articoli

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

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