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Documenti fondamentali

MAB2021Z

Sigma-Aldrich

Anti-Integrin αV Antibody, extracellular, clone AV1, azide free

culture supernatant, clone AV1, Chemicon®

Sinonimo/i:

CD51, VitronectinReceptor, MAB2021

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

AV1, monoclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Chemicon®

tecniche

flow cytometry: suitable
western blot: suitable

Isotipo

IgG1

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... ITGAV(3685)

Specificità

Specific for human integrin alphaV (other species not tested).

Immunogeno

Epitope: extracellular, azide free
Human integrin alphaVbeta3 heterodimer isolated from placenta.

Applicazioni

Anti-Integrin αV Antibody, extracellular, clone AV1, azide free detects level of Integrin αV & has been published & validated for use in FC & WB.
Flow cytometry: 1:5-1:50

Western Blot. Under non-reducing conditions recognizes a band at approximately 165 kDa corresponding to integrin alphaV. Does not recognize the reduced protein.

Function-blocking of integrin alphaV-mediated adhesion to ECM proteins. (1:5-1:20, in HEPES buffer pH 7.4 containing 1mM Mn++ and 1mM Mg++).

Optimal working dilutions and protocols must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Stato fisico

Unpurified tissue culture supernatant from a perfusion system, filtered through a 0.2μ micron membrane prior to vialing. Product contains 20%FBS and Ciprofloxacin at final concentration of 10μg/mL.

Stoccaggio e stabilità

Maintain at 2-8°C in undiluted aliquots for up to 12 months.

During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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A monoclonal antibody (ERIC-1), raised against retinoblastoma, that recognizes the neural cell adhesion molecule (NCAM) expressed on brain and tumours arising from the neuroectoderm
Bourne, SP et al.
Journal of Neuro-Oncology, 10, 111-119 (1991)
Integrin alpha8beta1 regulates adhesion, migration and proliferation of human intestinal crypt cells via a predominant RhoA/ROCK-dependent mechanism.
Yannick D Benoit,Carine Lussier,Pierre-Alexandre Ducharme,Sophie Sivret,Lynn M Schnapp et al.
Biology of the Cell null
Integrin alpha8beta1 confers anoikis susceptibility to human intestinal epithelial crypt cells.
Yannick D Benoit,Jean-Francois Larrivee,Jean-Francois Groulx,Jana Stankova et al.
Biochemical and biophysical research communications null
Human metapneumovirus (HMPV) binding and infection are mediated by interactions between the HMPV fusion protein and heparan sulfate.
Chang, A; Masante, C; Buchholz, UJ; Dutch, RE
Journal of virology null
Integrin alphavbeta1 promotes infection by human metapneumovirus.
Cseke, G; Maginnis, MS; Cox, RG; Tollefson, SJ; Podsiad, AB; Wright, DW; Dermody, TS; Williams, JV
Proceedings of the National Academy of Sciences of the USA null

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