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Key Documents

MAB16988

Sigma-Aldrich

Anti-Hepatitis B Virus Antibody, core Antigen, clone C1-5, a.a. 74-89

ascites fluid, clone C1-5, Chemicon®

Sinonimo/i:

HBcAg

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

300

Forma dell’anticorpo

ascites fluid

Tipo di anticorpo

primary antibodies

Clone

C1-5, monoclonal

Reattività contro le specie

human, avian

Produttore/marchio commerciale

Chemicon®

tecniche

ELISA: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG2aκ

Condizioni di spedizione

wet ice

Specificità

Reacts with HBcAg (epitope recognized - around amino acid positions 70-80, major C determinant).

SPECIES REACTIVITIES:

Cross-reacts with woodchuck hepatitis virus core antigen (WHcAg), but not with duck hepatitis B virus core antigen (DHcAg).

Immunogeno

Epitope: Core Antigen
Recombinant purified HBcAg from E.coli

Applicazioni

Anti-Hepatitis B Virus Antibody, core antigen, clone C1-5, a.a. 74-89 is an antibody against Hepatitis B Virus for use in ELISA, IF, IP, WB, IC, IH.
ELISA, immunoblotting, immunoprecipitation, immunofluorescent and immunoperoxidase staining of infected liver tissues and transfected cultured cells. Optimal working dilutions: for immunoblotting - 1:1000; for immunofluorescence - 1:200. Optimal working dilutions must be determined by the end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Stato fisico

Ascitic fluid. Liquid in DMEM, containing 0.1% sodium azide.

Stoccaggio e stabilità

Maintain at -20°C in undiluted aliquots for up to 12 months.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Assembly Pathway of Hepatitis B Core Virus-like Particles from Genetically Fused Dimers.
Holmes, K; Shepherd, DA; Ashcroft, AE; Whelan, M; Rowlands, DJ; Stonehouse, NJ
The Journal of Biological Chemistry null
A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly
Stray, Stephen J, et al
Proceedings of the National Academy of Sciences of the USA, 102, 8138-8143 (2005)
Cihan Makbul et al.
Microorganisms, 9(5) (2021-05-06)
Hepatitis B virus is a major human pathogen, which forms enveloped virus particles. During viral maturation, membrane-bound hepatitis B surface proteins package hepatitis B core protein capsids. This process is intercepted by certain peptides with an "LLGRMKG" motif that binds
Differentiation of core gene products of the hepatitis B virus in infected liver tissue using monoclonal antibodies
Naoumov, N V, et al
Journal of Medical Virology, 53, 127-138 (1997)
The structure of the variable regions of mouse monoclonal antibodies to hepatitis B virus core antigen.
Skrivelis, V, et al.
Scandinavian Journal of Immunology, 37, 637-643 (1993)
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