FCMAB207F

Milli-Mark^® Anti-CD71-FITC Antibody, clone Ber-T9

clone Ber-T9, Milli-Mark^®, from mouse

• Sinonimo/i: Transferrin receptor protein 1, TfR1, TfR, T9, p90
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Coniugato: FITC conjugate
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: Ber-T9, monoclonal
• Reattività contro le specie: human
• Produttore/marchio commerciale: Milli-Mark^®
• tecniche: flow cytometry: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_003225
• N° accesso UniProt: P02786
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... TFRC(7037)

Descrizione

Descrizione generale

CD71 is a 190 kDa disulfide-bonded homodimeric type II transmembrane glycoprotein. CD71 is the receptor for transferrin. CD71 is involved in iron (Fe3+) uptake, and expression is regulated by the metabolic demand for iron, which is essential for the growing cell (Goding, 2002). CD71 is more abundantly expressed in rapidly dividing cells than quiescent cells (Newman, 1982; Sutherland, 1981). In normal tissues, high expression of CD71 is seen in the placental trophoblast and hemoglobin-synthesizing reticulocytes (Newman, 1982) but expression is lost in mature erythrocytes (Sutherland, 1981). Anti-CD71, Ber-79, was included in the Fifth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD71 (Boeker, 1995).

Specificità

Antibody recognizes Human CD71 antigen.

Applicazioni

Detect CD71 using this Milli-Mark Anti-CD71-FITC Antibody, clone Ber-T9 validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Qualità

Evaluated by flow cytometry using human lymphocytes

Descrizione del bersaglio

190 kDa (Goding, 2002)

Stato fisico

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Stoccaggio e stabilità

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Risultati analitici

Control
Human Lymphocytes

Note legali

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable