ABN428

Anti-Fezf2 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Fez family zinc finger protein 2, Forebrain embryonic zinc finger-like protein 2, Zinc finger protein 312, Zinc finger protein Fez-like
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: rat, human, mouse
• Reattività contro le specie (prevista in base all’omologia): bovine (based on 100% sequence homology)
• tecniche: immunohistochemistry: suitable (paraffin); western blot: suitable
• N° accesso NCBI: NP_060478
• N° accesso UniProt: Q8TBJ5
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... FEZF2(55079)

Descrizione

Descrizione generale

Fezf2 is a transcriptional repressor protein. It is required for the specification of corticospinal motor neurons and other subcerebral projection neurons. FeZf2 also plays a role in the layer and subcortical specific patterning of the subcortical projections and axonal fasciculations that develop in the brain. Fezf2 also controls the development of the dendritic arborization and spines of the large layer V pyramidal neurons. Thus biological processes involving Fezf2 include neuronal patterning, differentiation, neurogenesis, axon guidance, fasciculation, cortex development, anterior/posterior patterning, dendrite development, and locomotory behavior, and it was recently identified as a multipotent progenitor marker for neocortical projection neurons, astrocytes, and oligodendrocytes.

Immunogeno

Epitope: Engrailed homology 1 repressor domain

KLH-conjugated linear peptide corresponding to the Engrailed homology 1 repressor domain of human Fezf2.

Applicazioni

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Fezf2 in rat spinal cord tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

This Anti-Fezf2 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Fezf2.

Qualità

Evaluated by Western Blotting in mouse E13-14 brain tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Fezf2 in 10 µg of mouse E13-14 brain tissue lysate.

Descrizione del bersaglio

~50 kDa observed

Stato fisico

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Altre note

Concentration: Please refer to lot specific datasheet.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable