476475

PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated

The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• Sinonimo/i: PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Myr-N-RKRTLRRL-OH, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated
• Formula empirica (notazione di Hill): C₆₀H₁₁₇N₂₁O₁₁
• Peso molecolare: 1308.71
• Codice UNSPSC: 12352202
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥97% (HPLC)
• Stato: lyophilized solid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; desiccated
• Solubilità: water: 5 mg/mL
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC₅₀ = 5 µM) in intact cells.

Azioni biochim/fisiol

Cell permeable: yes

Primary Target
PKC

Product does not compete with ATP.

Reversible: yes

Target IC₅₀: 5 µM against protein kinase C

Confezionamento

Yes

Attenzione

Toxicity: Standard Handling (A)

Sequenza

Myr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH

Stato fisico

Supplied as a trifluoroacetate salt.

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Altre note

Ward, N.E., and O’Brian, C.A. 1993. Biochemistry32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable