407653

Interleukin-6 Receptor, Soluble, Human, Recombinant, S. frugiperda

• Sinonimo/i: rhIL-6 sR
• Codice UNSPSC: 12352202
• NACRES: NA.42

Proprietà

• Saggio: ≥97% (SDS-PAGE)
• Livello qualitativo: 100
• Stato: lyophilized
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze
• Impurezze: ≤1 EU/μg Endotoxin
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −70°C

Descrizione

Descrizione generale

Recombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp 130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states, including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection.

Recombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection.

Azioni biochim/fisiol

ED₅₀= ≥5 ng/ml as measured by its ability to enhance IL-6-induced growth inhibition of mouse M1 myeloid leukemic cells

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

Lyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-6 receptor.

Ricostituzione

Reconstitute to a concentration ≥100 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.

Altre note

Schobitz, B., et al. 1995. FASEB J. 9, 659.
Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325.
Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078.
Lust, J.A., et al. 1992. Cytokine 4, 96.
Sugita, T., et al. 1990. J. Exp. Med. 171, 2001.
Yamasaki, K., et al. 1988. Science241, 825.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable