252926

N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt

Inhibitor of bacterial, viral, and mammalian neuraminidases. Ki = 4 µM for influenza virus neuraminidase. Believed to act by binding to the catalytic site of neuraminidase as a transition state analog.

• Sinonimo/i: N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt
• Formula empirica (notazione di Hill): C₁₁H₁₆NNaO₈
• Peso molecolare: 313.24
• Codice UNSPSC: 12352201
• NACRES: NA.79

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95% (TLC)
• Forma fisica: solid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; desiccated (hygroscopic)
• Colore: off-white to pale yellow
• Solubilità: water: 1 mM
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

A ganglioside neuraminidase inhibitor that is believed to act by binding to the catalytic site of neuraminidase. Reported to inhibit influenza virus neuraminidase (K_i = 4 µM). Also inhibits bacterial, viral, and mammalian neuraminidases.

Inhibitor of bacterial, viral, and mammalian neuraminidases. K_i = 4 µM for influenza virus neuraminidase. Believed to act by binding to the catalytic site of neuraminidase as a transition state analog.

Attenzione

Toxicity: Standard Handling (A)

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Altre note

Kopitz, J., et al. 1997. Eur. J. Cell. Biol.73, 1.
Holzer, C.T., et al. 1993. Glycoconj. J.10, 40.
Chong, A.K., et al. 1991. Biochem. Int.24, 165.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable