14-448-M

Cdk2/Cyclin A Protein, active, 10 µg

Active, C-terminal His6-tagged human full length Cdk2 & N-terminal GST-tagged human full length Cyclin A, for use in Kinase Assays.

• Codice UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.41

Proprietà

• Origine biologica: human
• Livello qualitativo: 100
• Ricombinante: expressed in baculovirus infected Sf21 cells
• Nome Commerciale: Upstate^®
• Attività specifica: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
• PM: M_w 35 kDa
• Purificato mediante: (The cdk2 is purified by Ni2+/NTA agarose and then activated using CAK and repurified by Q Sepharose and Ni2+/NTA agarose. The cyclin A is purified using glutathioneagarose)
• Reattività contro le specie: human
• Produttore/marchio commerciale: Upstate^®
• tecniche: activity assay: suitable (kinase)
• Numero d’accesso: (FUNCTION: SwissProt: P24941 # Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2. ); NM_001798.2
• N° accesso NCBI: NM_001798.2; NM_052827.1
• N° accesso UniProt: P24941

Descrizione

Descrizione generale

C-terminal His6-tagged human full length cdk2, and N-terminal GST-tagged human full length cyclin A

Azioni biochim/fisiol

Protein Target: CDK2/cyclinA

Target Sub-Family: CMGC

Confezionamento

Also available in 10 μg size and in bulk

Also available in 250μg size, please inquire for pricing and availability.

Qualità

routinely evaluated by phosphorylation of Histone H1

Descrizione del bersaglio

CDK2/cyclinA

Linkage

Replaces: 14-407

Stato fisico

The cdk2 is purified by Ni2+/NTA agarose and then activated using CAK and repurified by Q Sepharose^™ and Ni2+/NTA agarose. The cyclin A is purified using glutathioneagarose

Stoccaggio e stabilità

6 months at -70°C

Altre note

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Note legali

Sepharose is a trademark of Cytiva

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H317
• Consigli di prudenza: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classi di pericolo: Skin Sens. 1
• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°C): Not applicable