09-860

Anti-DDX3X Antibody

serum, from rabbit

• Sinonimo/i: ATP-dependent RNA helicase DDX3X, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked, DEAD box protein 3, X-chromosomal, DEAD box, X isoform, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, DEAD/H box-3, Helicase-like protein 2, helicase like protein 2
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• Clone: polyclonal
• application: WB
• Reattività contro le specie: mouse, human, rat
• tecniche: western blot: suitable
• citations: 3

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: serum
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: mouse, human, rat
• tecniche: western blot: suitable
• N° accesso NCBI: NP_001347.3
• N° accesso UniProt: O00571
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... DDX3X(1654)

Descrizione

Descrizione generale

DDX3X, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked, is a member of the DEAD box family of proteins. Characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), DEAD box proteins are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX3X is an ATP-dependent RNA helicase and acts as a co-factor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. DDX3X is also involved in HIV-1 replication and interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location.

Specificità

This antibody detects RNA-binding protein DDX3X.

Immunogeno

KLH-conjugated synthetic linear peptide corresponding to DDX3X.

Applicazioni

Research Category
Epigenetics & Nuclear Function

Research Sub Category
RNA Binding Protein (RBP)

Use Anti-DDX3X Antibody (Rabbit Polyclonal Antibody) validated in WB to detect DDX3X also known as ATP-dependent RNA helicase DDX3X, DEAD box protein 3 X-chromosomal.

Qualità

Evaluated by western blot on A431 cell lysate.

Western Blot Analysis: 1:1000 dilution of this antibody detected DDX3X in A431 cell lysate.

Descrizione del bersaglio

~73 kDa

Stato fisico

Rabbit polyclonal serum with 0.05% sodium azide.

Unpurified

Stoccaggio e stabilità

Stable for 1 year at -20ºC from date of receipt.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Risultati analitici

Control
A431 cell lysate

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1