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Merck
Tutte le immagini(1)

Documenti

07-614

Sigma-Aldrich

Anti-Surfactant Protein B Antibody

serum, Upstate®

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

serum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

mouse, human

Produttore/marchio commerciale

Upstate®

tecniche

immunohistochemistry: suitable
western blot: suitable

Isotipo

IgG

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

mouse ... Sftpd(20390)

Specificità

Surfactant Protein B

Immunogeno

Purified human surfactant protein B

Applicazioni

Anti-Surfactant Protein B Antibody is an antibody against Surfactant Protein B for use in IH & WB.
Research Category
Metabolism
Research Sub Category
Ion & Transport Channels

Qualità

routinely evaluated by immunoblot on human bronchiolar lavage fluid.

Descrizione del bersaglio

8kDa

Stato fisico

Serum
rabbit antiserum containing 0.05% sodium azide before the addition of glycerol to 30%

Stoccaggio e stabilità

2 years at -20°C

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Ralph Epaud et al.
American journal of respiratory cell and molecular biology, 28(3), 373-378 (2003-02-21)
Transgenic mice, in which the level of surfactant protein (SP)-B mature peptide varied 5.6-fold between SP-B(+/-) and SP-B-overexpressing lines (SP-B+/+/+), were used to test the hypothesis that SP-B protects against endotoxin-induced lung inflammation. Intratracheal administration of endotoxin resulted in significantly
Yan Liu et al.
Molecular reproduction and development, 84(8), 668-674 (2017-05-18)
Respiratory distress is a major cause of mortality in cloned neonatal animals, but its pathogenesis remains poorly understood. Here, we used necropsy and histology procedures to evaluate the lungs of cloned neonatal bovines dying of respiratory distress, finding incomplete lung
Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome.
Gregory, T J, et al.
The Journal of Clinical Investigation, 88, 1976-1981 (1991)
L M Nogee et al.
American journal of respiratory and critical care medicine, 161(3 Pt 1), 973-981 (2000-03-11)
Inability to produce surfactant protein B (SP-B) causes fatal neonatal respiratory disease. A frame-shift mutation (121ins2) is the predominant but not exclusive cause of disease. To determine the range of mechanisms responsible for SP-B deficiency, both alleles from 32 affected
Eileen L Whiteman et al.
Molecular and cellular biology, 34(1), 43-56 (2013-10-30)
First identified in Drosophila, the Crumbs (Crb) proteins are important in epithelial polarity, apical membrane formation, and tight junction (TJ) assembly. The conserved Crb intracellular region includes a FERM (band 4.1/ezrin/radixin/moesin) binding domain (FBD) whose mammalian binding partners are not

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