V-007

O-Desmethylvenlafaxine solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): C₁₆H₂₅NO₂
• Numero CAS: 93413-62-8
• Peso molecolare: 263.38
• Numero CE: 200-659-6
• Numero MDL: MFCD00871934
• Codice UNSPSC: 41116107
• ID PubChem: 329828919
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Livello qualitativo: 300
• Stato: liquid
• Caratteristiche: Snap-N-Spike^®/Snap-N-Shoot^®
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• Concentrazione: 100 μg/mL in methanol
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: clinical testing
• Formato: single component solution
• Temperatura di conservazione: −20°C
• Stringa SMILE: OC1=CC=C(C(CN(C)C)C2(O)CCCCC2)C=C1
• InChI: 1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3; KYYIDSXMWOZKMP-UHFFFAOYSA-N
• Informazioni sul gene: human ... SLC6A2(6530) , SLC6A4(6532)

Descrizione

Descrizione generale

An analytical reference standard applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications such as urine drug testing, forensic analysis, or clinical toxicology. Also known as desvenlafaxine, O-desmethylvenlafaxine is an SNRI antidepressant marketed under the trade name Pristiq^® for the treatment of depression. O-desmethylvenlafaxine is also a major urinary metabolite of venlafaxine, an SNRI antidepressant sold as Effexor^® or Efexor and used to treat major depressive disorder, generalized anxiety disorder, and other anxiety disorders associated with depression.

Applicazioni

• Drug Stability in Pharmaceutical Formulations: Another study focused on the physical stability and solubility of O-Desmethylvenlafaxine in various pharmaceutical formulations, contributing to better drug delivery systems and enhanced therapeutic efficacy (Wang et al., 2020).


• Monitoring Drug Precursors in Advanced Treatment Processes: Research monitored N-nitrosodimethylamine (NDMA) precursors throughout membrane-based advanced wastewater treatment processes, considering the behavior of compounds like O-Desmethylvenlafaxine. This study aids in improving wastewater treatment strategies to mitigate pharmaceutical pollutants (Roccaro et al., 2020).


• Chiral Drug Analysis in Environmental Waters: A study developed a dual enantioselective LC-MS/MS method for analyzing chiral drugs in surface water, including O-Desmethylvenlafaxine. This method helps in understanding the environmental fate and behavior of chiral pharmaceuticals, enhancing environmental risk assessments (Coelho et al., 2019).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Effexor is a registered trademark of American Home Product Corp.

Pristiq is a registered trademark of Wyeth LLC

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H301 + H311 + H331,H370
• Consigli di prudenza: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organi bersaglio: Eyes
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 49.5 °F - closed cup
• Punto d’infiammabilità (°C): 9.7 °C - closed cup